This work examines feasibility, practical advantages, and disadvantages of a combined MRI/magnetic particle hyperthermia (MPH) system for cancerous tumor treatment in low perfusion tissue. Although combined MRI/hyperthermia systems have been proposed and constructed, the current proposal differs because the hyperthermia system would be specifically designed to interact with the magnetic nanopar...

Bone Tumor Suppression Magnetic bone cement incorporating magnetically soft zinc ferrite nanoparticles and aligned in a direct current magnetic field realized exceptionally high heating power live animals under clinically safe parameters for hyperthermia. of osteosarcoma rabbits by hyperthermia substantially enhances survival rate. More details can be found article number 2104626 Shuli He, Qing...

A range of lanthanum strontium manganates (La1−xSrxMnO3–LSMO) where 0 ≤ x < 0.4 were prepared using a modified peroxide sol–gel synthesis method. The magnetic nanoparticle (MNP) clusters obtained for each of the materials were characterised using scanning electron microscopy (SEM), X-ray powder diffraction (XRD) and infra-red (IR) spectroscopy in order to confirm the crystalline phases, crystal...

Metallic nanostructures show unique physical and chemical properties compared to their bulk counterparts due to their high surface area to volume ratio. For instance, magnetic nanoclusters (NCs) show superparamagnetic behavior only when they are below a certain critical size [1]. In addition, intrinsic magnetic properties such as the Curie temperature (Tc), saturation magnetization (Ms), and co...

Several species of Magnetotactic bacteria have been discovered recently. These bacteria synthesize intracellular magnetic nanoparticles in specific sizes and shapes and arrange them in chains. These particles called magnetosomes and can be used for drug-delivery, cell-targeting and hyperthermia. Magnetotactic bacteria navigate along the magnetic field; this process is known as ‘magnetotaxis’ wh...

Magnetic nanoparticle (MNP)-based magnetic resonance imaging (MRI) contrast agents (CAs) have been the subject of extensive research over recent decades. The particle size of MNPs varies widely and is known to influence their physicochemical and pharmacokinetic properties. There are two commonly used methods for synthesizing MNPs, organometallic and aqueous solution coprecipitation. The former ...

An effective therapeutic approach against cancer typically requires the combination of several modalities, such as chemotherapy, radiation, and hyperthermia. In this regard, the development of multifunctional nanomaterial-based systems with combined therapeutic and molecular imaging capabilities has shown great potential but has not been fully explored. In particular, magnetic nanomaterials hav...

Superparamagnetic iron oxide nanoparticles (SPIONs) are promising tools for the treatment of different diseases. Their magnetic properties enable therapies involving magnetic drug targeting (MDT), hyperthermia or imaging. Depending on the intended treatment, specific characteristics of SPIONs are required. While particles used for imaging should circulate for extended periods of time in the vas...

Encapsulated Fe3O4 nanoparticles of average diameters d = 12 nm are obtained by coprecipitation, in the presence of 2-methoxyethanol hemiester of poly(maleic anhydride-alt-butyl vinyl ether) 5% grafted with poly(ethylene glycol) (VP-MAG nanoparticles). A complete characterization of nude and encapsulated nanoparticles through structural techniques (namely XRD, TEM, SEM), Raman spectroscopy and ...

Our purpose in this study was to present an integral-transform approach to the analytical solutions of the Pennes' bioheat transfer equation and to apply it to the calculation of temperature distribution in tissues in hyperthermia with magnetic nanoparticles (magnetic hyperthermia). The validity of our method was investigated by comparison with the analytical solutions obtained by the Green's f...