INTRODUCTION Comprehensive pain management services are primarily located in urban areas, limiting specialist consultation opportunities for community healthcare providers. A community of practice (CoP) for pain management could create opportunities for consultation by establishing professional relationships between community healthcare providers and pain management specialists. A CoP is a grou...

BACKGROUND Footwear-generated biomechanical manipulations have been shown to alter lower limb kinetics. It has been suggested that this is due to altered trajectory of the foot's center of pressure (COP), conveying a shift in location of the ground reaction force and modifying moments and forces acting on proximal body segments. However, past studies have focused on qualitative association betw...

Aghighi and Bäckström have previously studied cost-optimal planning (COP) and net-benefit planning (NBP) for three action cost domains: the positive integers (Z+), the nonnegative integers (Z0) and the positive rationals (Q+). These were indistinguishable under standard complexity analysis for both problems, but separated for COP using parameterised complexity analysis. With the plan cost, k, a...

Copolymer 1 (Cop 1, poly (Y, E, A, K)) is a random synthetic amino acid copolymer effective in the treatment of relapsing forms of multiple sclerosis (MS). Cop 1 binds promiscuously, with high affinity and in a peptide-specific manner to purified MS-associated HLA-DR2 (DRB1*1501) and rheumatoid arthritis-associated HLA-DR1 (DRB1*0101) or HLA-DR4 (DRB1*0401) molecules. In the present work at lea...

We investigate the role of the information available to the players on the outcome of the cops and robbers game. This game takes place on a graph and players move along the edges in turns. The cops win the game if they can move onto the robber’s vertex. In the standard formulation, it is assumed that the players can “see” each other at all times. A graph G is called cop-win if a single cop can ...

We consider cop-win graphs in the binomial random graph G(n, 1/2). We prove that almost all cop-win graphs contain a universal vertex. From this result, we derive that the asymptotic number of labelled cop-win graphs of order n is equal to (1 + o(1))n2 2/2−3n/2+1.

Recent data strongly suggest that the coatomer (COP) complex is involved in membrane transport between the ER and Golgi complex. This vesicular coat has been implicated in ER to Golgi, in intra Golgi as well as in Golgi to ER traffic. In this study we present a detailed immunocytochemical analysis of the distribution of β-COP in different tissue culture cells. Our results extend previous studie...