objective(s): in this study, drug loaded electrospun nanofibrous mats were prepared and drug release and mechanism from prepared nanofibers were investigated.  materials and methods: paclitaxel (ptx) loaded polylactic acid (pla) nanofibers were prepared by electrospinning. the effects of process parameters, such as ptx concentration, tip to collector distance, voltage, temperature and flow rate...

PEGylated polypropyleneimine (PPI) dendritic scaffold was used for the delivery of an anti-leukemic drug, Imatinib. The current study evolves and emerges the use PEGylated PPI dendritic scaffold for the delivery of this drug. In this Imatinib was synthesized and loaded with PEGylated PPI dendritic scaffold. Parameters such as FT-IR, NMR, SEM, drug release, DSC and hemolytictoxicity are required...

PEGylated polypropyleneimine (PPI) dendritic scaffold was used for the delivery of an anti-leukemic drug, Imatinib. The current study evolves and emerges the use PEGylated PPI dendritic scaffold for the delivery of this drug. In this Imatinib was synthesized and loaded with PEGylated PPI dendritic scaffold. Parameters such as FT-IR, NMR, SEM, drug release, DSC and hemolytictoxicity are required...

this study examines the controlled release behavior of both water-soluble (acetaminophen, caffeine, theophylline and salicylic acid) and water insoluble (indomethacin) drugs derived from caesalpinia pulcherrima seed gum isolated from caesalpinia pulcherrima kernel powder. it further investigates the effect of incorporating diluents such as microcrystalline cellulose and lactose on caffeine rele...

     The aim of this study is to prepare novel sorbitol based extended release tablets by melt dispersion method using carbamazepine as a model drug. Carbamazepine was melted along with sugar alcohol to get melt dispersion granules (MGDs) and was characterized by differential scanning calorimetry (DSC), powder X-ray diffractometry (XRD) and solubility study. The physical and chemical parameters...

In this study, the synthesis, characterization and controlled release behavior of new Hollow Silica Nano particles (HSNPs) and Magnetic Silica Nano Particles (MSNPs) were studied. Magnetic Silica Nano particles (MSNPs), as drug delivery vehicles, were synthesized through the coating of Fe3O4 nano-crystals with silica layers. The HSNPs were obtained by removal of Fe3O4 templates with hydrochlori...

the aim of this study was to develop a derivative of chitosan as pharmaceutical excipient used in sustained-release matrix tablets of poorly soluble drugs. a water-soluble quaternary ammonium carboxymethylchitosan was synthesized by a two-step reaction with carboxymethylchitosan (cmcts), decylalkyl dimethyl ammonium and epichlorohydrin. the elemental analysis showed that the target product with...

In this paper, carbon nanotubes (CNTs) were added into chitosan (CS) hydrogels in the form of chitosan modified CNTs (CS-CNTs) composites to prepare carbon nanotubes hydrogels (CNTs-GEL). The products, named CS-MWCNTs, were characterized by scanning electron microscope (SEM) and Fourier transform infrared (FTIR) spectroscopy. Swelling properties and effect of pH on controlled release performanc...