Marriage is said to be consanguineous, when it is between persons descending from the common ancestor. Consanguineous marriages are widely contracted worldwide despite the devastating effects in children born to such couples. The aim of the study was to analyze the impact of consanguinity on hearing in babies born out of consanguineous marriages. It was a comparative study in 50 children aged b...

To test the effects of parental consanguinity on mortality among offspring, inbreeding coefficients were estimated for 303,675 members of the Utah Mormon population who were born between 1847 and 1945. Although consanguinity has been relatively rare in this population, the large sample size permitted the identification of more than 3,500 inbred offspring. Among the offspring of unrelated parent...

Genetic service for couples plays an increasingly important role in diagnosis and risk management. This study investigated the status of consanguinity and the medical genetic history (effectiveness and coverage of medical genetic services) in couples residing in a city in southern Iran. We questioned couples who were referred to Behbahan Marital Counseling Center, Behbahan, Iran, during the per...

OBJECTIVES To describe the characteristics and prevalence of non-syndromic orofacial clefting (NSOFC) and assess the effects of parental consanguinity on NSOFC phenotypes in the 3 main cities of Saudi Arabia. METHODS All infants (114,035) born at 3 referral centers in Riyadh, and 6 hospitals in Jeddah and Madinah between January 2010 and December 2011 were screened. The NSOFC cases (n=133) we...

SCD is one of the major health problems in Saudi Arabia, especially in Southern, Western and Eastern areas where the gene frequency of this disease is quite prevalent. Many studies were carried out in these areas. There is a lack of studies of the effect of consanguinity on disease outcome and prognosis. We did this study in western area in Almadinah Almunawarah. We determined the effect of con...

The rarity of consanguineous marriage in much of the industrialized world, and the current restriction or outright prohibition of first-cousin unions in a majority of US states and in East Asian countries such as China, North and South Korea and the Philippines, has led many commentators to overlook the fact that the Out-of-Africa migration some 60,000–70,000 years ago had been undertaken by qu...

Consanguinity, marriage between relatives, has been associated with perinatal mortality and morbidity. Apnea of prematurity is defined as the cessation of breathing for longer than 20 seconds or that of any duration if accompanied by cyanosis and sinus bradycardia, for infants born before 37 weeks of gestation. The objective of the study was to examine the association between consanguinity and ...

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1: The evidence base for intervention with respect to smoking and consanguinity. Meta-analyses reveal that passive smoking and consanguinity ARE both risk factors in OFC. Mossey, P.A. “Passive smoking in the etiology of non-syndromic orofacial clefts: a systematic review and meta-analysis”. Sabbagh HJ, Hassan MH, Innes NP, Elkodary HM, Little J, Mossey PA Data extraction from studies reporting ...

Background Consanguinity has been suggested as a risk factor for the development of schizophrenia in offspring in some Middle Eastern countries. Aim The purpose of this study was to review the frequency, pattern of parental consanguinity, and family history of schizophrenia among schizophrenia patients in Qatar, and to determine their impact on the associated risk factors. Design This is a cros...