Background: Diminished ovarian reserve (DOR) is a heterogeneous disorder causing infertility, characterized by a decreased number of oocytes and high FSH level, the genetic cause of which is still unknown. The association between FMR1 premutations(50-200 CGG repeats) and the premature ovarian failure( POF) disease has suggested that FMR1 gene acts as a risk factor for POF and recently for DOR p...

conclusions this study showed that the presence of mutation at codons rtl80v, rtl180m and rtm204v in a, b and c domains is associated with higher viral load and resistance to lamivudine (3tc) respectively. results about 6% (3 of 50) of samples were hbeag positive and 94% (47 of 50) of patients were hbeag negative by elisa method. the patients' alt level was between 16 and 95 iu/l with the mean ...

Gammaherpesvirus pathogenesis is dependent on the ability of these viruses to establish a lifelong latent infection and the ability to reactivate from latency. Immediate-early genes of theses viruses are thought to be critical regulators of lytic replication and reactivation from latency. The gene 50-encoded Rta is the only immediate-early gene product that appears to be conserved among all cha...

Motion is ubiquitous in the physical world, yet its study is much less developed than that of another common physical modality, namely shape. While we have several standardized mathematical shape descriptions, and even entire disciplines devoted to that area–such as Computer-Aided Geometric Design (CAGD)—the state of formal motion descriptions is still in flux. This in part because motion descr...

AbstractBackground COVID-19 has been associated with Interstitial Lung Disease features. The immune transcriptomic overlap between Idiopathic Pulmonary Fibrosis (IPF) and not investigated. Methods we analyzed blood transcript levels of 50 genes known to predict IPF mortality in three two cohorts. Scoring Algorithm Molecular Subphenotypes (SAMS) was applied distinguish...