Getting to the inner circle ontiguity between the ER and the nuclear envelope means nuclear membrane proteins have a direct shot to their target. In fact, inner nuclear membrane (INM) proteins were thought to need only to diffuse to the nucleus, pass through the nuclear pore, and then be retained by nuclear-localized binding partners. But new results suggest a more active process. Suraj Saksena...

The theory of circle packings and, more generally, of circle patterns enjoys in recent years a fast development and a growing interest of specialists in complex analysis and discrete mathematics. This interest was initiated by Thurston’s rediscovery of the Koebe-Andreev theorem [K] about circle packing realizations of cell complexes of a prescribed combinatorics and by his idea about approximat...

Given a combinatorial description C of a polyhedron having E edges, the space of dihedral angles of all compact hyperbolic polyhedra that realize C is generally not a convex subset of R [9]. If C has five or more faces, Andreev’s Theorem states that the corresponding space of dihedral angles AC obtained by restricting to non-obtuse angles is a convex polytope. In this paper we explain why Andre...