PURPOSE In conjunctival melanoma, tumor thickness and nonlimbal location are associated with poor prognosis. However, other established high-risk features for cutaneous melanoma, including ulceration, mitotic figures, epithelioid cell type, and lymphovascular invasion, have not previously been studied extensively for their prognostic value in conjunctival melanoma. We examined the hypothesis th...

PURPOSE Antigen-sampling M cells have been identified in conjunctival tissue overlying lymphoid follicles in rabbits and guinea pigs. Conjunctival M cells in the guinea pig display alpha(2-3) sialic acid on their surfaces, as evinced by selective labeling by Maackia amurensis leukoagglutinin (MAL)-I. Haemophilus influenzae strains OM12, which expresses the HMW1 adhesin for alpha(2-3) sialic aci...

This report describes a unique case of coexisting necrobiotic xanthogranuloma and chronic lymphocytic leukemia in a patient presenting with scleritis and uveitis. A 53-year-old Caucasian man diagnosed with anterior uveitis and scleritis for the prior year was referred to our uveitis clinic for further evaluation. Prior uveitis/scleritis workup performed by the referring ophthalmologist was nega...

Purpose To investigate the incidence and peak elevation of conjunctival prolapse during short-term open eye scleral lens wear its association with fitting characteristics. Methods Ten young, healthy adults (mean age ± SD, 30 4 years) wore a high Dk sealed for 90 min an initial central post-lens fluid reservoir thickness defined as low (144 23 ?m), medium (487 63 (726 55 ?m). Optical coherence t...

The masquerade syndrome was first described by Theodore (1), and Irvine (2) independently in 1967, as chronic blepharoconjunctivitis due to an underlying conjunctival carcinoma. Conjunctival intraepithelial neoplasia and sebaceous cell carcinoma have been reported to show intraepithelial (pagetoid) spread to the conjunctiva mimicking chronic blepharoconjunctivitis, or cicatrizing conjunctivitis...

BACKGROUND To present a case of conjunctival lymphoma in a young woman complicated by pregnancy. CASE PRESENTATION A 38-year-old previously healthy woman presented with a 2-year history of progressive right blepharoptosis. Giant papillomatous sessile masses were identified in the upper and lower fornix bilaterally and involved the tarsus of the right upper lid. The remaining ophthalmic examin...

The dispersal of pigment centrifugally through the conjunctiva from the site of a repaired traumatic perforation was observed. Iris tissue had been incarcerated in the wound for three days prior to surgical repair. Conjunctival biopsies were examined by light and electron microscopy. Light microscopy revealed a normal, non-pigmented conjunctival epithelium and numerous pigment-laden cells in th...

The accuracy of the Surecell Chlamydia Test Kit (Kodak Clinical Products, Rochester, N.Y.) in detecting neonatal conjunctival infection caused by Chlamydia trachomatis was determined by comparison of this enzyme immunoassay with the isolation of C. trachomatis in tissue culture. Kodak Surecell is a rapid monoclonal antibody-based membrane capture enzyme immunoassay which can be processed in the...