Congenital infection with Zika virus causes microcephaly and other brain abnormalities (1). Hearing loss associated with other congenital viral infections is well described; however, little is known about hearing loss in infants with congenital Zika virus infection. A retrospective assessment of a series of 70 infants aged 0-10 months with microcephaly and laboratory evidence of Zika virus infe...

BACKGROUND Congenital toxoplasmosis presents as severe, life-altering disease in North America. If mothers of infants with congenital toxoplasmosis could be identified by risks, it would provide strong support for educating pregnant women about risks, to eliminate this disease. Conversely, if not all risks are identifiable, undetectable risks are suggested. A new test detecting antibodies to sp...

BACKGROUND Toxoplasma infection during pregnancy exposes the fetus to risks of congenital infection and sequelae that depend heavily on gestational age (GA) at time of infection. Accurate risk estimates by GA are necessary to counsel parents and improve clinical decisions. METHODS We analyzed data from pregnant women diagnosed with acute Toxoplasma infection in Lyon (France) from 1987 to 2008...

Recurrent meningitis occurs usually due to immunological or anatomical abnormality as well as chronic parameningeal infections. Anatomical abnormalities can be acquired or congenital and most of them are located in the head and neck region. Congenital defects include inner ear abnormalities, patent cochlear aqueduct, patent Hyrtlʼs fissure, abnormal developed facial canal and dehiscence at the ...

CONFLICT OF INTEREST none declared. INTRODUCTION Authors are from reference documentation to archive at Organization of Federation of blind and visually impaired in central Serbia (Kragujevac), by retrograde analysis, of 2007-2012, comprehend two groups by etiology-clinical characteristics of congenital blindness and visually impaired, caused infection or non infection example. AIM to analy...

It is over 50 years since a syndrome of congenital abnormalities following maternal rubella infection was first recognised. Despite the potentially devastating effects of the congenital rubella syndrome, immunisation rates are not optimal and infections in pregnancy still occur. Four cases of rubella infection occurring in pregnancy are presented. Laboratory diagnosis of primary infection and r...

While infections and malnutrition are the dominant causes of infant morbidity and mortality in the poorer countries of the world, 1 in the developed countries these causes are cancer, accidents and congenital malformations. 2,3 In Saudi Arabia, a rich and fast-developing nation with a very effective expanded program on immunization, childhood malnutrition has virtually been eradicated and infec...

Isolated pulmonary vein atresia without associated congenital malformation is a very rare condition in adults. It is associated with significant mortality and morbidity. Recurrent pulmonary infections, dyspnea on exertion and hemoptysis may be the presenting complaints. Owing to the limited number of patients with this condition there may be some difficulties in it's diagnosis and therapy. We r...

Dear Editors, The paper by van der Linden et al., “Discordant clinical outcomes of congenital Zika virus infection in twin pregnancies”1 provides additional information in a story that has placed Zika firmly in the company of other infections such as cytomegalovirus and toxoplasmosis that can cause birth defects in the central nervous system. Unlike these other congenital infections, however, Z...