BACKGROUND: The preliminary survey made about congenital goiter in goats in Garmsar township indicated that the disease occurs much more in Beetal-cross than native goats raised in the same area. OBJECTIVES: The aim of the present study was to compare of serum triiodothyronine (T3), tetraiodothyronine (T4) and thyroid stimulating hormone concentrations in pregnant and lactating Beetal-cross and...

Objective: To evaluate the impact of salt iodization on the prevalence of goiter among school children in the city of Shiraz. Design: In 1989, prior to initiation of universal salt iodization in Iran, 2419 male and female students, 6-18 years were randomly selected and evaluated for the presence of goiter, which was graded according to WHO goiter classification. A similar study was carried out ...

OBJECTIVE This cross-sectional study was conducted in Ahwaz, Iran to find out the prevalence of goiter among schoolchildren ages 11-16 years. SUBJECTS AND METHODS Multistage sampling methodology was followed for selecting the study population. A total of 1,950 children (1,050 males, 900 females) were clinically assessed for thyroid gland enlargement. Data were collected on age, sex, weight, h...

CONTEXT Thyroglobulin (TG) gene mutations cause congenital hypothyroidism (CH) with goiter. A founder effect has been proposed for some frequent mutations. Mutated proteins have a defect in intracellular transport causing intracellular retention with ultrastructural changes that resemble an endoplasmic reticulum storage disease. OBJECTIVE To reveal new aspects of thyroglobulin pathophysiology...

Goiter or thyromegaly is one of the most common causes of mid tracheal obstruction (external compression or stenosis), which may be associated with difficult larynx visualization and/or difficult airway management, depending on the goiter size, type and ingrowth into the surrounding tissue. Iodine deficiency disorders are still one of the most common causes of goiter in the population of the Af...