The coronavirus disease 2019 (COVID-19) have devastated the globe and continues to be a protracted saga. In absence of specific efficacious medical remedies, efforts encounter contain this emerging virus concentrated on vaccine production. A plethora novel vaccines has been under development by major companies in different countries. To date, around 60 are clinical trials with many other ones c...

Recently, the prevalence of Fasciola hepatica in some areas has increased considerably and the availability of a vaccine to protect livestock from infection would represent a major advance in tools available for controlling this disease. To date, most vaccine-target discovery research on this parasite has concentrated on proteomic and transcriptomic approaches whereas little work has been carri...

We revisit earlier attempts for finding matrix exponential (ME) distributions of a given order with low coefficient of variation (cv). While there is a long standing conjecture that for the first non-trivial order, which is order 3, the cv cannot be less than 0.200902 but the proof of this conjecture is still missing. In previous literature ME distributions with low cv are obtained from special...

BACKGROUND An estimated 4% of global child deaths (approximately 300,000 deaths) were attributed to rotavirus in 2010. About a third of these deaths occurred in India and Ethiopia. Public finance of rotavirus vaccination in these two countries could substantially decrease child mortality and also reduce rotavirus-related hospitalizations, prevent health-related impoverishment and bring signific...

WORK has been directed recently towards the development of a freeze-dried BCG vaccine with the property of heat stability in order to provide a vaccine which will retain its potency if exposed for short periods to the high environmental temperatures experienced in tropical countries. Numerous attempts have been made to improve the heat stability of freeze-dried BCG vaccine. Earlier attempts hav...