Recent advances, such as the availability of extensive genome survey sequence (GSS) data and draft physical maps, are radically transforming the means by which we can dissect Brassica genome structure and systematically relate it to the Arabidopsis model. Hitherto, our view of the co-linearities between these closely related genomes had been largely inferred from comparative RFLP data, necessit...

Computational social science is a new emerging field that has overlapping regions from mathematics, psychology, computer sciences, sociology, and management. Social computing is concerned with the intersection of social behavior and computational systems. It supports any sort of social behavior in or through computational systems. It is based on creating or recreating social conventions and soc...

this paper presents a new mathematical model for the problem of scheduling part families and jobs within each part family in a flow line manufacturing cell where the setup times for each family are sequence dependent and it is desired to minimize the maximum completion time of the last job on the last machine (makespan) while processing parts (jobs) in each family together. gaining an optimal s...

Interactions between DNA and proteins are central to living systems, and characterizing how and when they occur would greatly enhance our understanding of working genomes. We review the different computational problems associated with protein-DNA interactions and the various methods used to solve them. A wide range of topics is covered including physics-based models for direct and indirect reco...

Erectile dysfunction (ED) is defined as the inability to achieve and maintain an erection adequate for satisfactory intercourse. It is a common problem among approximately 50% of men between the ages of 40 and 70. Erectile dysfunction is not only stressful to both the affected individual and his partner, but it can also negatively affect self-esteem. Biomechanical models have recently been deve...

We introduce a notion of training methodology space (TM space) for specifying training methodologies in tile different disciplines and teaching traditions associated with computational linguistics and the human language technologies, and pin our approach to the concept of operational model; we also discuss different general levels of interactivity. A number of operational models are introduced,...

Executing large number of self-regulating tasks or tasks that execute minimal inter-task communication in analogous is a common requirement in many domains. In this paper, we present our knowledge in applying two new Microsoft technologies Dryad and Azure to three bioinformatics applications. We also contrast with traditional MPI and Apache Hadoop MapReduce completion in one example. The applic...

1National Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing 100875, China 2Department of Electrical and Electronic Engineering, Imperial College London, London SW7 2AZ, UK 3Department of Informatics, King’s College London, London WC2R 2LS, UK 4School of Information Engineering, Nanchang University, Nanchang 330031, China 5Intelligent Systems and Biomedica...

In this paper we describe a unified framework for the computation of power series expansions of invariant manifolds and normal forms of vector fields, and estimate the computational cost when applied to simple models. By simple we mean that the model can be written using a finite sequence of compositions of arithmetic operations and elementary functions. In this case, the tools of Automatic Dif...