INTRODUCTION Although 90% of prostate cancer is considered to be localized, 20%-30% of patients will experience biochemical failure (BF), defined as serum PSA >0.2 ng/mL, after radical prostatectomy (RP). The presence of circulating prostate cells (CPCs) in men without evidence of BF may be useful to predict patients at risk for BF. We describe the frequency of CPCs detected after RP, relation ...

Mechanisms of cardiac pacemaking and conduction system (CPCS) development are difficult to study, in part because of the absence of models that are physiologically similar to humans in which we can label the entire CPCS. Investigations of the adult rabbit heart have provided insight into normal and abnormal cardiac conduction. The adult and the embryonic rabbit have an endogenous marker of the ...

RATIONALE Pluripotent stem cell-derived cardiac progenitor cells (CPCs) have emerged as a powerful tool to study cardiogenesis in vitro and a potential cell source for cardiac regenerative medicine. However, available methods to induce CPCs are not efficient or require high-cost cytokines with extensive optimization due to cell line variations. OBJECTIVE Based on our in-vivo observation that ...

Several studies have demonstrated a multiphasic role for Wnt signaling during embryonic cardiogenesis and developed protocols that enrich for cardiac derivatives during in vitro differentiation of human pluripotent stem cells (hPSCs). However, few studies have investigated the role of Wnt signaling in the specification of cardiac progenitor cells (CPCs) toward downstream fates. Using transgenic...

Aim. Physicochemical mechanical and in vitro biological properties of novel formulations of polymeric calcium phosphate cements (CPCs) were investigated. Methods. Monocalcium phosphate, calcium oxide, and synthetic hydroxyapatite were combined with either modified polyacrylic acid, light activated polyalkenoic acid, or polymethyl vinyl ether maleic acid to obtain Types I, II, and III CPCs. Sett...

Every year, more than 2.2 million bone grafting procedures are performed worldwide. Bone tissue engineering seeks to develop strategies to heal bone loss due to disease without the drawbacks and impediments of existing clinical autografting and allografting treatments [1]. One of the most promising groups of synthetic bone replacements is calcium phosphate cements (CPCs). Due to the similarity ...

BACKGROUND We have recently found that 3 repeated doses (12×106 each) of c-kitPOS cardiac progenitor cells (CPCs) were markedly more effective than a single dose of 12×106 cells in alleviating postinfarction left ventricular dysfunction and remodeling. However, since the single-dose group received only one third of the total number of CPCs given to the multiple-dose group, it is unknown whether...

It is well-known that concentrators are sparse graphs of high connectivity, which play a key role in the construction of switching networks; and any semi-vertex transitive graph is isomorphic to a bi-coset graph. In this paper, we prove that random bi-coset graphs are almost always concentrators, and construct some examples of semi-vertex transitive concentrators.

The paper presents two designs of combined prismatic-parabola-cylindrical stationary concentrators. They reach 8.4X and 10.4X concentration levels for nonsymmetrical and symmetrical concentrators correspondingly and can be used with solar cells for electricity and heat generation. ©2010 Optical Society of America OCIS codes: (220.1770) Concentrators; (220.4298) Nonimaging optics; (220.2740) Geo...