Introduction: For centuries, cannabinoids are known to be effective in pain relief. Itch is an unpleasant sensation that provokes a desire to scratch. Since itch and pain are two sensations sharing a lot in common, we aimed to investigate whether the cannabinoid agonist WIN 55,212-2 reduces serotonin-induced scratching behavior and also observe whether modulation of nitric oxide (NO) production...

Early life stress (ES) significantly increases predisposition to psychopathologies. Cannabinoids may cause cognitive deficits and exacerbate the effects of ES. Nevertheless, the endocannabinoid system has been suggested as a therapeutic target for the treatment of stress- and anxiety-related disorders. Here we examined whether cannabinoids administered during "late adolescence" (extensive canna...

INTRODUCTION Previous studies have shown that cannabinoidergic system is involved in anxiety. However, there are controversial reports in the experimental studies. The aim of this study is to evaluate the effect of pharmacological stimulation or blocking of CB1 receptors and inhibition of endocannabinoid degradation in anxiety like behavior in elevated plus-maze (EPM) test in rat. The EPM is on...

Companies spend enormous resources on customer relationship management (CRM), but there is no clear understanding on two seemingly simple, but critical questions: (1) Should firms reward or punish their current customers? (2) Can CRM be profitable in a competitive setting? While CRM practitioners are enthusiastic about its win-win potential for firms and customers, the extant theoretical litera...

BACKGROUND The impact of metabolic and reproductive features of polycystic ovary syndrome (PCOS) compromises psychological functioning. We investigated factors associated with negative psychological functioning to determine whether they were predictive of anxiety and depression in PCOS. METHODS A cross-sectional study was performed by questionnaire in 177 women with PCOS (mean ± SD age 32.8 ±...

Learning Problem Solving Methods in order to Reduce Stress and Anxiety, and Increase Achievement Motivation T. Aboutalebi Ahmadi Learning to solve problems can help reduce anxiety and stress on the one hand, and increase chances of success, on the other. A sample of 78 freshmen at a teacher training college was randomly selected from among 156, and then divided into two groups of ...

Objective: This study is an examination of the relationship between self-compassion, cognitive anxiety, somatic anxiety, and self-confidence as competitive state anxiety among female athletes Students. Methodology: The research method was descriptive-correlational. Two hundred and fifty-three female student (140 taekwondo and 113 karate) were selected among athletes present at the 14th Student ...

Previous studies have demonstrated that an external focus can enhance motor learning compared to an internal focus. The benefits of adopting an external focus are attributed to the use of less effortful automatic control processes, while an internal focus relies upon more effort-intensive consciously controlled processes. The aim of this study was to compare the effectiveness of a distal extern...