نتایج جستجو برای: common variable immunodeficiency cvid
تعداد نتایج: 1013055 فیلتر نتایج به سال:
Common variable immunodeficiency (CVID) is a heterogeneous disorder that is associated with low serum-immunoglobulin concentrations, defective specific-antibody production and an increased susceptibility to bacterial infections of the respiratory and gastrointestinal tracts. In spite of the identification of genes that are associated with several known primary immunodeficiencies, the basic immu...
common variable immunodeficiency (cvid) is a heterogeneous heritable disease characterized by arrest in b cell differentiation. an association between cvid and two hla haplotypes, haplotype i (hla-a1, hla-b8, hla-dr3) and haplotype ii (hla-a29, hla-b44, hladr7)has been previously documented. in the present study, we have attempted to find an association between susceptibility to cvid and hla cl...
Common Variable Immunodeficiency Disorders (CVIDs) are the most prevalent cause of primary antibody failure. CVIDs are highly variable and a genetic causes have been identified in <5% of patients. Here, we performed whole genome sequencing (WGS) of 34 CVID patients (94% sporadic) and combined them with transcriptomic profiling (RNA-sequencing of B cells) from three patients and three healthy co...
Common variable immunodeficiency (CVID) is the most common symptomatic in adults. This study assessed utility of using C-reactive protein (CRP)/albumin ratio (CAR) at diagnosis to predict mortality CVID patients. Between 2010 and 2022, hospital records follow-up cards patients with were reviewed retrospectively. Seventy-five included study. CRP 0–5 mg/L albumin 3.5–5.5 g/dL taken as references....
BACKGROUND Common variable immunodeficiency (CVID) is a primary immunodeficiency disease characterized by recurrent infections and increased susceptibility to autoimmunity and malignancy. OBJECTIVES This study was performed to estimate the burden of CVID in Iran during 1985-2008 based on incidence, mortality, and disability-adjusted life-years (DALY). METHODS The methods developed by the Wo...
Late onset combined immunodeficiency (LOCID) is a recently described variant of common variable immunodeficiency (CVID), involving adult patients presenting with opportunistic infections and/or low CD4+ lymphocyte counts. A 36-year-old male with unremarkable past medical history presented with fever, respiratory failure, and lymphocytopenia. He was found to have Pneumocystis jiroveci pneumonia ...
BACKGROUND AND PURPOSE Common variable immunodeficiency (CVID) is a primary immunodeficiency disorder, which presents with hypogammaglobulinemia and recurrent bacterial infections. Patients with CVID have frequent and severe episodes of pneumonia. The standard intravenous immunoglobulins (IVIG) therapy has led to the reduction of pulmonary infections in these patients. The aim of this study was...
The aim of the present study was to investigate to what extent interstitial lung disease (ILD) in common variable immunodeficiency disorder (CVID)-associated granulomatous disease (GD) is similar to pulmonary sarcoidosis 20 patients with CVID/GD were included in a retrospective study conducted by the Groupe Sarcoïdose Francophone. Medical records were centralised. Patients were compared with 60...
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