1 2 August 3, 2012 3 Revised: August 6, 2012 4 5 Quantitative Phosphoproteomics in Nuclei of Vasopressin-Sensitive 6 Renal Collecting Duct Cells 7 8 9 Steven J. Bolger*, Patricia A. Gonzales Hurtado*, Jason D. Hoffert, Fahad Saeed, Trairak 10 Pisitkun, and Mark A. Knepper 11 12 *Co-First Authors 13 14 Epithelial Systems Biology Laboratory, 15 NHLBI, National Institutes of Health, 16 Bethesda, M...

Informatics and AI claim that the word is made of objects organized into classes (taxonomies, ontologies,...). In this paper, we explore an other idea: we structure our material relationships by collecting objects within collections, which are never as static as classes.

Given a set of points P in the plane and profits (or prizes) π : P → R≥0 we want to select a maximum profit set X ⊆ P which maximizes P p∈X π(p) − μ(X) for some particular criterion μ(X). In this paper we consider four such criteria, namely the perimeter and the area of the smallest axis-parallel rectangle containing X, and the perimeter and the area of the convex hull conv(X) of X. Our key res...

While highly effective, psychotherapy outcome studies suggest 5-14% of clients worsen while in treatment and that therapists are unable to identify a substantial portion of such cases. Methods to systematically collect feedback from psychotherapy clients are discussed and two systems for monitoring treatment response, feeding back this information, and assisting in problem-solving with such cas...