By NICoi S COSTEA, VINCENT YAKULLS AND PAUL HELLER H EMOLYTIC ANEMIA of the cold agglutinin ( CA ) variety is believed to represent an autoimmune disorder occasionally complicating the course of lymphoproliferative diseases.’2 Whereas animal models have been proposed for the investigation of various autoimmune phenomena,3 cold reacting erythrocyte autoantibodies have not yet been studied in exp...