there is an impression that basal cell carcinomas (bcc) occurring in younger population may be of more invasive behavior in comparison to those arising in older patients. the purpose of this study was to investigate this hypothesis by comparing the histological types of bcc in a large cohort of young and old patients. a total of 287 histological reports and clinical records were evaluated. a co...

BACKGROUND Genetics and early environment are known to influence height, but evidence is sparse on changes in these influences over time. METHODS The 1958 British birth cohort study includes all children born between March 3, 1958 and March 9, 1958, who were followed to age 41 yr, and one-third of their offspring in 1991. Childhood height in each generation (measured at 7 yr for cohort member...

The aim of this study was to verify the agreement between different approaches for estimating levels of physical activity in adolescents. One questionnaire was administered to parents and two were administered to the adolescents. This was a cross-sectional analysis of data collected in the 2004-2005 follow-up of the 1993 Pelotas (Brazil) birth cohort study. Parents or guardians answered the fol...

Population-based, prospective longitudinal cohort studies are considering the issues surrounding returning findings to individuals as a result of genomic and other medical research studies. While guidance is being developed for clinical settings, the process is less clear for those conducting longitudinal research. This paper discusses work conducted on behalf of The UK Cohort and Longitudinal ...

This article examines the development of the educational and vocational careers of 1257 subjects born between 1961 and 1969 as a function of economic circumstances in the Netherlands during the eighties. Subjects were expected to attend school longer in times of recession, to have a higher level of education, while getting a suitable, high-quality job (in terms of number of hours, appointment t...

in many area of medical research, a relation analysis between one response variable and some explanatory variables is desirable. regression is the most common tool in this situation. if we have some assumptions for such normality for response variable, we could use it. in this paper we propose a nonparametric regression that does not have normality assumption for response variable and we focus ...

background: data on premature coronary artery disease (cad) are scarce. the tehran heart center's premature coronary atherosclerosis cohort study (thc-pac) is the first study of its kind in the middle east to assess major adverse cardiac events (mace) in young cad patients. methods: the cohort consists of cad patients, males ≤ 45 years old and females ≤ 55 years old. the participants are reside...

background : this study aimed to investigate the association of seven common inflammatory diseases with type 2 diabetes (t2d) in the chinese mainland population. methods : participants were recruited from a great swathe of mainland from 2009 to 2013 for the cohort study. the demographic characteristics between patients with t2d or with inflammatory diseases, including age, sex, smoking status, ...