نتایج جستجو برای: cochlear damage

تعداد نتایج: 241120  

2013
ANTJE ASCHENDORFF

Introduction: Different Perimodiolar electrodes were developed by many cochlear implant (CI) manufacturers in the past few years. Possible advantages are lower stimulation thresholds and a better channel separation. A position close to the modiolus can be facilitated by different means: preformed electrode shape (Nucleus ContourTM electrode, Cochlear Corp., Australia), additional positioning el...

2014
Noritaka AIHARA Shingo MURAKAMI Mariko TAKAHASHI Kazuo YAMADA

We classified the results of preoperative auditory brainstem response (ABR) in 121 patients with useful hearing and considered the utility of preoperative ABR as a preliminary assessment for intraoperative monitoring. Wave V was confirmed in 113 patients and was not confirmed in 8 patients. Intraoperative ABR could not detect wave V in these 8 patients. The 8 patients without wave V were classi...

Journal: :Hearing research 2017
Gavin M Bidelman Amy D Schneider Victoria R Heitzmann Shaum P Bhagat

Human hearing sensitivity is easily compromised with overexposure to excessively loud sounds, leading to permanent hearing damage. Consequently, finding activities and/or experiential factors that distinguish "tender" from "tough" ears (i.e., acoustic vulnerability) would be important for identifying people at higher risk for hearing damage. To regulate sound transmission and protect the inner ...

2017
Azadeh Jadali Yu-Lan M. Ying Kelvin Y. Kwan

The sensory hair cells of the inner ear are exquisitely sensitive to ototoxic insults. Loss of hair cells after exposure to ototoxic agents causes hearing loss. Chemotherapeutic agents such as cisplatin causes hair cell loss. Cisplatin forms DNA mono-adducts as well as intra- and inter-strand DNA crosslinks. DNA cisplatin adducts are repaired through the DNA damage response. The decision betwee...

2015
Sonam Dilwali Lukas D. Landegger Vitor Y. R. Soares Daniel G. Deschler Konstantina M. Stankovic

Vestibular schwannomas (VSs) are the most common tumours of the cerebellopontine angle. Ninety-five percent of people with VS present with sensorineural hearing loss (SNHL); the mechanism of this SNHL is currently unknown. To establish the first model to study the role of VS-secreted factors in causing SNHL, murine cochlear explant cultures were treated with human tumour secretions from thirtee...

Journal: :Hearing research 1992
A B Greenberg M W Myers D O Hartshorn J M Miller R A Altschuler

Cochlear implants are being applied to an ever widening patient population, including children in whom lifetime use of these devices is anticipated. Replacement of implants can be expected for reasons of device failure as well as future upgrading. This investigation was undertaken to examine the effect of cochlear electrode explanation and reimplantation on spiral ganglion cell survival. Guinea...

Journal: :The Journal of laryngology and otology 2007
O F Adunka C A Buchman

OBJECTIVE To demonstrate the feasibility and complexities of cochlear implantation in the setting of bilateral temporal bone osteoradionecrosis. STUDY DESIGN Case report. SETTING Tertiary care referral centre. CASE DESCRIPTION A 66-year-old woman with bilateral temporal bone osteoradionecrosis and profound hearing loss, following treatment for tonsillar cancer, underwent cochlear implanta...

Journal: :ORL; journal for oto-rhino-laryngology and its related specialties 2002
Henryk Skarzyński Artur Lorens Patrick D'Haese Adam Walkowiak Anna Piotrowska Lech Sliwa Ilona Anderson

OBJECTIVE To investigate whether the residual hearing of severely hearing-impaired children and adults could be preserved using the soft surgery approach. PATIENTS AND METHODS This project employed a prospective study design. All testing and surgery took place in the Institute of Physiology and Pathology of Hearing, Warsaw, Poland. Twenty-six patients (7 children and 19 post-lingually deafene...

Journal: :The international tinnitus journal 2005
Leonard P Rybak

Platinum-containing drugs, such as cisplatin and carboplatin, are known to have ototoxic side effects causing hearing loss that may be accompanied by tinnitus. This study reviews recent studies on the ototoxicity of cisplatin and carboplatin and summarizes the effects of protective agents that may prevent hearing loss and tinnitus. The primary locus of ototoxicity is in the cochlea, but oxidati...

2014
Ryan J Longenecker Kurt T Chonko Steve M Maricich Alexander V Galazyuk

Tinnitus is a maladaptive neuropathic condition that develops in humans and laboratory animals following auditory insult. In our previous study we demonstrated that sound exposure leads to development of behavioral evidence of tinnitus in a sample of exposed mice. However, this tinnitus mouse model did not account for long-term maladaptive plasticity or aging, factors that are commonly linked t...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید