Objective Osteopontin (Opn) is one of the co-factors which participates in cell adhesion and invasion during implantation process. Increased incidence of spontaneous abortion is reported in diabetic women. Several reports have shown Opn gene expression changes in diabetic condition in several tissues. Therefore, this study was designed to evaluate the effects of diabetes on Opn gene expression ...

Long-chain acyl-CoA synthases (LACSs) are a key factor in the formation of after fatty acid hydrolysis and play an important role plant stress resistance. This gene family has not been research soybeans. In this study, soybean (Glycine max (L.) Merr.) whole genome was identified, LACS genes were screened, bioinformatics, tissue expression, abiotic stress, drought co-expression transcription fac...

Gene co-expression is of great importance to scientists studying biology and molecular biology. To make sense of expression datasets, we present a tool, CORNEA, to create and visualize large co-expression networks. These networks allows end users to explore gene co-expression relationsships for large datasets with many genes. CORNEA is implemented as a web service at Lotus Base and the tool is ...

Gene co-expression networks can be used to associate genes of unknown function with biological processes, to prioritize candidate disease genes or to discern transcriptional regulatory programmes. With recent advances in transcriptomics and next-generation sequencing, co-expression networks constructed from RNA sequencing data also enable the inference of functions and disease associations for ...

spermatogonial stem cells (sscs) maintain spermatogenesis throughout life in the male. maintenance of sscs and induction of spermiogenesis in vitro may provide a therapeutic strategy to treat male infertility. this study investigated in vitro differentiation of mouse sscs in presence or absence of sertoli cells, hormones and vitamins. spermatogonial populations were enriched from testes of 4-6 ...

objective: tooth loss is a common problem and since current tooth replacement methods cannot counter balance with biological tooth structures, regenerating natural tooth structures has become an ideal goal. a challenging problem in tooth regeneration is to find a proper clinically feasible cell to seed.this study was designed to investigate the odontogenic potential of human bone marrow mesench...

abiotic stress are the main factors causing low growth and yield in crops. osmotic stress is an important stress and in case of salinity stress is presuming at the first step. there are different experimental and computational methods to study plant response to stress and lead to better understanding of mechanism involved in these conditions and improvement of plant tolerance to stress. upstrea...

 Objective: In obesity, chronic low grade inflammation, created by induction of pro-inflammatory markers, causes adipocyte dysfunction in adipose tissue. Adipocytes dysfunction is associated with various diseases including insulin resistance and obesity. In obesity, inflammatory factors such as osteopontin (OPN), angiopoietin-like protein 2 (Angptl2) and transforming growth factor-β (TGF-β) are...