نتایج جستجو برای: cns malignancies
تعداد نتایج: 142476 فیلتر نتایج به سال:
thrombin is a multifunctional enzyme which has key roles in coagulation cascade and inflammatory events. the pro-inflammatory functions of thrombin occur by different mechanisms including increasing mast cell degranulation, up-regulating the expression of cell adhesion molecules (cams) and promoting the secretion of inflammatory chemokines and cytokines. dysregulated signaling functions of thro...
The mortality of central nervous system (CNS) aspergillosis approaches 100%, requiring improved therapies. Voriconazole gives superior efficacy and survival in invasive aspergillosis, compared with amphotericin B. Also, in contrast to other antifungal drugs, voriconazole penetrates well into the CNS. We evaluated, retrospectively, the outcome and survival of 81 patients who were treated with vo...
The mortality of central nervous system (CNS) aspergillosis approaches 100%, requiring improved therapies. Voriconazole gives superior efficacy and survival in invasive aspergillosis, compared with amphotericin B. Also, in contrast to other antifungal drugs, voriconazole penetrates well into the CNS. We evaluated, retrospectively, the outcome and survival of 81 patients who were treated with vo...
Following the first CNS Anticancer Drug Discovery and Development Conference, the speakers from the first 4 sessions and organizers of the conference created this White Paper hoping to stimulate more and better CNS anticancer drug discovery and development. The first part of the White Paper reviews, comments, and, in some cases, expands on the 4 session areas critical to new drug development: p...
BACKGROUND Tumours of the central nervous system (CNS) account for 15-20% of all malignant childhood tumours in developed countries. Steady improvement of survival of children with CNS tumours has been reported for the past decades. However, these results, obtained by cohort analysis of survival, do not reflect the full extent of recent improvement. METHODS Using selected registries from the ...
Medulloblastoma is the most prevalent malignant brain tumor in children, accounting for roughly 15% to 20% of all malignancies Central Nervous System (CNS), 40% childhood, tumors are posterior fossa. a heterogeneous combination several subgroups with discrete characteristics, rather than homogeneous illness. Genomic profiling medulloblastomas revealed that medulloblastoma may be further divided...
r t o c t r h a w n b p n unanticipated consequence of recent successes in the treatment of non–central nervous system (CNS) malignancies has been a steady ncrease in the frequency of brain and spinal fluid elapse. This pattern has been well-documented in paients with breast cancer, small cell and non-small cell ung cancer, and non-Hodgkin lymphoma (NHL) and ay well emerge in other common (colo...
In the December issue of Liver Transplantation, Durand et al. extensively reviewed the issue of extended criteria donors in liver transplantation. They mentioned the problem of donors with a history of malignancy and recommended in Table 2 that donors with grade III/IV central nervous system (CNS) malignant tumors be rejected as the risk of malignancy transmission is estimated at 40%. This esti...
neurocysticercosis, is the infection caused by the larval form of the tapeworm taenia solium. it is considered as the most common parasitic disease of the central nervous system and the most common cause of acquired epilepsy. this has primarily been a disease that remains endemic in countries with poor economy , but because of increased migration neurocysticercosis is being diagnosed more frequ...
abstract objective tumors of the central nervous system constitute the largest group of solid neoplasms in children and are second only to leukemia in their overall frequency during childhood. the main purpose of the present study is to determine the incidence, age, sex, location and histological diagnosis of cns tumors in children, less than 15 years of age, in the mofid children's hospital, i...
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