introduction:torch infections causing via toxoplasma gondii, other microorganisms (e.g., treponema pallidum), rubella virus, cytomegalovirus (cmv) and the herpes simplex virus (hsv) types 1 and 2 during the first trimester of pregnancy can lead to severe fetal anomalies or even fetal loss. the current study determined the serological data of torch infections in women who were in their first tri...

Congenital cytomegalovirus (CMV) infection is a leading cause of hearing, cognitive, and motor disability in children for which medical science has yet to provide prevention or cure. Although vaccines aimed at prevention of congenital infection are being developed, there are significant challenges to be overcome and it could easily be a decade or longer before a CMV vaccine is licensed for prev...

We report here the results of a study on the prenatal diagnosis of congenital cytomegalovirus (CMV) infection. The study was carried out by both PCR and virus isolation from amniotic fluid (AF) for 82 pregnant women at risk of transmitting CMV for the detection of (i) seroconversion to CMV immunoglobulin G (IgG) positivity during the first trimester of pregnancy, (ii) symptomatic CMV infection ...

Infectious mononucleosis (IM) is mostly caused by Epstein-Barr virus (EBV) while IM by cytomegalovirus (CMV) is rather rare. In our retrospective clinical research with multiplex virus PCR analysis, we encountered 6 cases of CMV-IM and analyzed the clinical characteristics including diagnostic problems. The diagnosis of CMV-IM was made when the CMV genome was solely detected from the patient’s ...

OBJECTIVE This study was undertaken to determine the prevalence of congenital cytomegalovirus (CMV) infection in pregnant women at the end of pregnancy in Kuwait using cord blood and maternal urine. SUBJECTS AND METHODS Urine samples were collected prior to childbirth, and cord blood was collected immediately after delivery from 983 women. Anti-CMV IgG and IgM antibodies were determined using...

The titres of IgG antibody against "late antigens", "immediate early antigens", and "early antigens" induced by cytomegalovirus (CMV) and IgM antibody against "late antigens" induced by CMV were analysed in 67 geriatric subjects by immunocytochemical techniques. The titres obtained were compared with those of an adult control population. Significantly increased titres of IgG antibody against in...

Four hundred and forty-one blood and serum samples were collected during August to October 1998 from the blood donors at the blood bank of Rajvithi Hospital, Bangkok, Thailand. Their ages were varied between 18-55 years. All specimens were tested by immunostaining and ELISA methods. Forty-seven specimens (10.66%) gave positive results by immunostaining. Among these, 20 cases were seropositive a...

OBJECTIVES This study aimed to compare polymerase chain reaction (PCR) and IgM detection using enzyme linked immune-sorbent assay (ELISA) in diagnosis of congenital cytomegalovirus (CMV) infection. METHODS This study was conducted from May 2009 to December 2010. Urine and blood samples were collected from 94 neonates with suspected congenital CMV infection. Serum and part of urine samples wer...

Cytomegalovirus is one of the opportunistic infections associated with significantly high morbidity and mortality among patients living with immunodeficiency syndrome. Cytomegaloviruses (CMV) are deoxyribonucleic acid (DNA) viruses and are members of the Herpesviridae family CMV are recognized pathogens that cause community-acquired pneumonia (CAP) in compromised hosts. We investigated the prev...