Potential conflicts of interest: none reported. The views expressed in this commentary are those of the author and do not necessarily reflect the official policy or position of the Connecticut Department of Public Health. The article by Doolan et al. in this issue of the Journal of Infectious Diseases [1] describes the immune responses to anthrax among persons exposed and possibly exposed when ...

INTRODUCTION Influenza is a major respiratory viral infection of humans with high mortality and morbidity rates and profound economic impact. Although influenza vaccines are generally updated yearly to match the viruses expected in the coming season, genetic mutation and reassortment can result in unexpected novel strains. Therefore, it is important to develop universal vaccines inducing protec...

We discuss a simple definition of conditional mutual information (CMI) for fields and σ-fields. The new definition is applicable also in nonregular cases, unlike the well-known but more restricted definition of CMI by Dobrushin. Certain properties of the two notions of CMI and their equivalence for countably generated σ-fields are established. We also consider an application, which concerns the...

BACKGROUND In veterinary clinical pain studies, there is a paucity of data on test-retest variability in Clinical Metrology Instruments (CMIs), and it is unknown whether CMIs should be administered using independent (respondents not permitted to see previous answers) or dependent (respondents shown previous answers) interviewing. OBJECTIVES To compare baseline variability in CMIs designed to ...

Both varicella and herpes zoster (HZ) can cause severe disease in certain age groups. The cell-mediated immune (CMI) response to the varicella zoster virus (VZV) is critical in preventing a recurrence of VZV. The varicella vaccine has markedly decreased the morbidity and mortality associated with varicella, but concerns linger about the cost and frequency of vaccine administration and the long-...

BACKGROUND United States retail pharmacies are key sources of written consumer medication information (CMI) through leaflets dispensed with prescription drugs. The content and format of this CMI are unregulated. Public Law 104-180 stipulates that by 2006, 95% of prescriptions be accompanied by "useful" CMI. METHODS Professional shoppers filled prescriptions for lisinopril and metformin in a n...

Mice suppress the parasitemia of acute blood-stage Plasmodium chabaudi malaria by an antibody- or T-cell-dependent cell-mediated mechanism of immunity (AMI and CMI, respectively) or by both mechanisms. To determine whether CD28 costimulation is required for expression of these polar immune responses, we first compared the time courses of P. chabaudi malaria in CD28-deficient (CD28(-/-)) and CD2...

1. Introduction The Collaboration Management Infrastructure (CMI) has been developed at MCC to manage collaboration processes in both traditional and virtual enterprises, and to provide combined process and situation awareness. CMI technology development is driven by the requirements of many advanced applications provided by the companies that are members of the consortial CMI project. Such adv...

The Youth Level of Service/Case Management Inventory-Screening Version (YLS/CMI-SV) is designed to provide a preliminary estimate of the level of risk for antisocial behaviors as well as an indication of areas for intervention in youth offenders. This study examined the predictive validity of the YLS/CMI-SV for violent, nonviolent, and general recidivism in a sample of 3,264 youth offenders wit...