Prevention of red cell K+ and water loss is a therapeutic strategy for sickle cell disease. We have investigated in vitro and in vivo the effects of clotrimazole (CLT) and miconazole (MIC) on transgenic mice red cells expressing hemoglobin SAD. CLT blocked the Gardos channel (ID50 75 +/- 22 nM; n = 3) and the A23187-induced dehydration of Hbbs/Hbbthal SAD 1 mouse erythrocytes in vitro. Oral tre...

Query learning models from computational learning theory (CLT) can be adopted to perform elicitation in combinatorial auctions. Indeed, a recent elicitation framework demonstrated that the equivalence queries of CLT can be usefully simulated with price-based demand queries. In this paper, we validate the flexibility of this framework by defining a learning algorithm for atomic bidding languages...

a positive integer $n$ is called a clt number if every group of order $n$ satisfies the converse of lagrange's theorem‎. ‎in this note‎, ‎we find all clt and supersolvable numbers up to $1000$‎. ‎we also formulate some questions about the distribution of these numbers‎.

background and purpose: candida species are the most opportunistic fungi affecting the nails and resulting in onychomycosis. in this study, we identified and evaluated in-vitro susceptibility of the recovered isolates against fluconazole (flc), voriconazole (vrc), and clotrimazole (clt) using the clinical and laboratory standards institute (clsi) m27-a3 document. materials and methods: from pat...

PURPOSE To establish a standard clinical procedure for measuring intraocular pressure (Po) with the contact lens tonometer (CLT), to demonstrate possibilities for analyzing ocular pulsation and performing ophthalmodynamometry. METHODS A reliable histogram-based analyzing system for determining Po is used. First, the ocular pressure was registered with the CLT method and compared with the Gold...

Growing evidence from online credibility research reveals that online users rely on heuristic processes to evaluate the credibility of online information. The current paper, which is based on the construal level theory (CLT), proposes that congruency between the psychological distance of a stimulus and the way it is mentally construed can act as a heuristic for believability. According to CLT, ...

At Crypto 2013, Coron, Lepoint, and Tibouchi (CLT) proposed a practical Graded Encoding Scheme (GES) over the integers, which has very similar cryptographic features to ideal multilinear maps. In fact, the scheme of Coron et al. is the second proposal of a secure GES, and has advantages over the first scheme of Garg, Gentry, and Halevi (GGH). For example, unlike the GGH construction, the subgro...

Language proficiency in bilingualism, and hence bilingual aphasia, is a multifaceted phenomenon: influenced by variables such as age of onset, literacy, usage patterns, and emotional valence. Although the majority of the world and growing US population is bilingual, relatively little is known about the best practices for language therapy in bilingual aphasia. This systematic review was undertak...

A new variant of CLT is established for random elds de ned on Rd which are strictly stationary, with nite second moment and weakly dependent (comprising cases of positive or negative association). The summation domains grow in the van Hove sense. Simultaneously the indices of observations form more and more dense grids in these domains. Thus the e ect of combining two scaling procedures is stud...

For at least four decades there has been concern about the discontinuity between the discipline and practice of nursing. The learning traditions in nursing, including the traditional organization of professional educational curricula with an emphasis on general education, could be contributing to this discontinuity. Problem Based Learning (PBL) has been identified as one way to facilitate great...