Editing is a general event in plant mitochondrial messenger RNAs, but has never been detected in a plant mitochondrial transfer RNA (tRNA). We demonstrate here the occurrence of a tRNA editing event in higher plant mitochondria: in both bean and potato, the C encoded at position 4 in the mitochondrial tRNA(Phe)(GAA) gene is converted into a U in the mature tRNA. This nucleotide change corrects ...

the clivus is the surface of a portion of the occipital and sphenoid bones in the base of the skull. (1)it is surrounded by the neurovascular structures of the brainstem, as well as internal carotid arteries. tumors of the clivus can be benign (chordoma)or malignant (chondrosarcoma).(2) chordomas are rare, aggressive, slow-growing, invasive, and locally destructive tumors that arise from the no...

ollier’s syndrome, a variant of multiple enchondromatosis, is a rare disease with an estimated prevalence of 1/100,000, characterized by multiple enchondromas, asymmetrically involving small bones of the hands and feet, especially the proximal phalanges. intracranial enchondromas, such as those arising from the skull base are extremely rare. herein, we report a 25-year-old female, known case of...

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skeletal involvement is the second most common site of metastases after lymph nodal metastases in patients with prostate cancer. the skeletal metastases from prostate cancer are osteoblastic in nature and show increased tracer avidity on the bone scan. focal tracer avid lesion in skeleton especially in skull requires the careful examination by further investigation. the patients with skull meta...

Domain I is a cloverleaf-like secondary structure at the 5' termini of all enterovirus genomes, comprising part of a cis-acting replication element essential for efficient enteroviral replication. 5' genomic terminal deletions up to as much as 55% of domain I can occur without lethality following coxsackie B virus infections. We report here that the entire CVB structural domain I can be deleted...

The 5' UTR of Coxsackievirus B3 (CVB3) contains internal ribosome entry site (IRES), which allows cap-independent translation of the viral RNA and a 5'-terminal cloverleaf structure that regulates viral replication, translation and stability. Here, we demonstrate that host protein PSF (PTB associated splicing factor) interacts with the cloverleaf RNA as well as the IRES element. PSF was found t...