The aim of this work was to develop a novel (99m)Tc-labelled derivative based on triphenylethylene for breast cancer imaging. (99m)Tc-Clomiphene was obtained with a radiochemical yield of 94.4% by adding (99m)Tc to 1.5 mg Clomiphene citrate in the presence of 10 μg SnCl(2) at pH 7. The optimization of the labeling yield of Clomiphene citrate, with (99m)Tc, is described. The reaction parameters ...

polycystic ovary syndrom (pcos) is characterized by infertility, oligomenorrhea, and hyperandrogenism. clomiphene citrate (cc), an antiestrogen, is first-line treatment for pcos, if cc fails to induce ovulation, laparascopic electrocautery of the ovaries is offered. in this prospective controlled study, 52 women with clomiphen-resistant pcos (group 1) and 46 women with regular menstrual cycles ...

objective: to compare the effectiveness of letrozole and clomiphene citrate (cc) on uterine blood flow rate in patients with unexplained infertility. materials and methods: in this randomized clinical trial 90 women with unexplained infertility referred to a university clinic from january 2011- december 2013 were enrolled. thirty patients were randomized for letrozole, 30 patients for cc and 3o...

BACKGROUND Polycystic ovary syndrome (PCOS) is the most common cause of infrequent periods (oligomenorrhoea) and absence of periods (amenorrhoea). It affects about 4% to 8% of women worldwide and often leads to anovulatory subfertility. Aromatase inhibitors (AIs) are a novel class of drugs that were introduced for ovulation induction in 2001. Over the last ten years clinical trials have reached...

BACKGROUND Poor ovarian response to controlled ovarian stimulation is one of the most important interest points in assisted reproduction. Mild ovarian stimulation seems to be preferable to high dose of FSH regimens in women with a history of poor ovarian response in previous protocol. Clomiphene citrate and letrozole alone or in combination with FSH have been used in mild ovarian stimulation pr...

The outcome of ovulation induction in anovulatory polycystic ovarian syndrome (PCOS) may depend, in part, on the pharmacologic compounds used, but also on individual patient characteristics, such as age, body mass index (BMI), hyperandrogenism, luteinizing hormone (LH), hyper-secretion, anti mullerian hormone (AMH) levels and possibly antral follicle count (AFC) with ovarian volume of these wom...