Macrophages are an essential component of antitumor activity; however, the role tumor-associated macrophages (TAMs) in colorectal cancer (CRC) remains controversial. Here, we elucidated TAMs CRC progression, especially at early stage. We assessed TAM number, phenotype, and distribution 53 patients with neoplasia, including intramucosal submucosal invasive (SM-CRC), advanced cancer, using double...

The spectrum of lipomatous lesions ranges from benign to highly malignant disease. Differentiation between these mesenchymal is important for pathologist as well clinician indicate prognosis and choose the most appropriate treatment. Hemosiderotic firohistiocytic tumor (HFLT) a rare subtype tumor. diagnosis usually based on clinical, histological, immunohistochemical (IHC) information. We repor...

Introduction: Early recurrence of hepatocellular carcinoma (HCC) is a major risk factor affecting survival even after hepatectomy. Many clinical, biochemical parameters and pathological grading like fibrosis 1 index have been used for risk stratifying HCC. However not many studies have combined all of them. It is therefore important to risk stratify HCC especially with newer PE...

Anaplastic large cell lymphoma (ALCL) is a mature T cell lymphoma with characteristic morphologic, immunophenotypic and cytogenetic features. Current WHO classification includes anaplastic lymphoma kinase (ALK)positive and ALK-negative variants. ALCL rarely presents with obstructive symptoms of the main airway. In addition to reporting a HIV-associated bronchial ALK-negative ALCL in a 44 year-o...

We report the clinical and histopathological findings in two patients who had undergone treatment of facial contour abnormalities with the injectable microimplant Dermalive. Both patients presented after approximately 18 months with subcutaneous clearly palpable indurations and nodules in the area of previous augmentation. Histopathological examination of the partially excised lesions showed fe...

1 Characteristic 0 We start with a basic question: given a polynomial f ∈ C[z1, · · · , zn] with a singularity at 0, how can we measure the “singularness” of this polynomial in a precise way? In other words: we can look at various singularities and see intuitively that some singularities are worse than others. For instance, it feels like a transverse self-intersection is probably not as bad as ...

OBJECTIVE To evaluate the relation between argyrophilic nucleolar organizer region (AgNOR)-associated proteins and clinicopathological parameters and survival in non-small-cell lung cancer (NSCLC). METHODS A total of 207 surgical specimens diagnosed as NSCLC were included in this study. Double-staining procedures were performed using antigen Ki-67 (clone MIB-1) and silver nitrate by immunohis...