Abnormalities of the uterine cavity can be a contributing cause of subfertility, and assessment of this factor has been suggested as a routine investigation in the evaluation of subfertile women. Hysterosalpingography has been used as the most common procedure in the investigation of infertility cause. Saline infusion sonohysterography can show uterine cavity abnormalities, which is highly sens...

Meta-analyses have found conflicting results with respect to the use of progesterone or progesterone plus estrogen as luteal phase support for in vitro fertilization (IVF) protocols involving gonadotropins and/or gonadotropin-releasing hormone analogs. The aim of the present study was to perform an updated meta-analysis on the efficacy of progesterone versus progesterone plus estrogen as luteal...

OBJECTIVE To investigate whether pre-eclampsia is more common in first pregnancies solely because fewer affected women, who presumably have a higher risk of recurrence, go on to have subsequent pregnancies. DESIGN Prospective cohort study. SETTING Swedish Medical Birth Register. PARTICIPANTS 763 795 primiparous mothers who had their first births in Sweden, 1987-2004. MAIN OUTCOME MEASUR...

background: clomiphene citrate (cc) an agonist and antagonist of estrogen, is the first line treatment in ovarian stimulation. anti-estrogenic effect of cc in endometrial thickness and cervical mucus has negative effect on pregnancy rate. letrozole is an aromatase inhibitor has been seen that has acceptable pregnancy rate compared to cc. objective: the aim of this study was to compare the effic...

The aim of this study was to investigate the relationships among the ages of patients, serum progesterone (P) levels on the day of human chorionic gonadotropin administration (DHCG), and clinical pregnancy rates in a gonadotropin-releasing hormone (GnRH)-agonist long protocol. A total of 5,566 patients followed at the reproductive medicine center of a tertiary care public hospital who were unde...

BACKGROUND Advanced maternal age (AMA) is an important parameter that negatively influences the clinical pregnancy rate in IVF, in particular owing to the increased embryo aneuploidy rate. It has thus been suggested that only transferring euploid embryos in this patient group would improve the pregnancy rate. The purpose of this study was to test whether employing preimplantation genetic screen...

oocyte activation (aoa), results in high fertilization rates. objective: this prospective, randomized, unblinded clinical study aimed to evaluate the efficiency of calcium ionophore on fertilization and pregnancy rate after intracytoplasmic sperm injection (icsi) in infertile men suffer from teratoospermia. materials and methods: thirty eight women with teratoospermic partner underwent icsi wit...

BACKGROUND The aim of this study is to assess the effect of body mass index (BMI) on outcomes of in vitro fertilization (IVF) / intracytoplasmic sperm injection (ICSI) among polycystic ovarian syndrome (PCOS) and non-PCOS patients. METHODS This was a retrospective cohort study that was performed in the Second Hospital of Hebei Medical University. Patients who were under 35 years old were incl...

background: to compare a flexible, multi-dose gnrh antagonist protocol with a long gnrh .agonist protocol in poor respo materials and methods: a randomized clinical trial of 70 poor responder patients (35 patients in gnrh antagonist protocol and 35 patients in long gnrh agonist protocol) was performed at royan institute, tehran, iran. both groups were given a fixed dose of human menopausal gona...

background: although the uterine fibroids are common, their influence on fertility remains controversial. the association of submucosal fibroid with subfertility is well recognized, but debate persists as to whether intramural fibroids can cause infertility and the evidence for its effect on pregnancy in cycles of assisted conception remains unclear. objective: the purpose of present study was ...