OBJECTIVE To evaluate the efficacy comparison of Pueraria mirifica (PM), name in Thai is Kwao Kruea Khao, against conjugated equine estrogen (CEE) with/without medroxyprogesterone acetate (MPA) in the treatment of perimenopuasal women with climacteric symptoms. MATERIAL AND METHOD Perimenopausal women attending the Menopausal clinic of Hat Yai Regional Hospital were voluntarily recruited. The...

OBJECTIVES Gerontological research suggests that depressive symptoms show antecedent and consequent relations with late-life disability. Less is known, however, about how depressive symptoms change with the progression of disability-related processes and what factors moderate such changes. METHODS We applied multiphase growth models to longitudinal data pooled across 4 Swedish studies of very...

OBJECTIVE Menopause is an important life event that may have a negative influence on quality of life. Work ability, a concept widely used in occupational health, can predict both future impairment and duration of sickness absence. The aim of this study was to examine the impact of menopausal symptoms on work ability. METHODS This was a cross-sectional study that used a sample of healthy worki...

PURPOSE This study was conducted to investigate the efficacy of black cohosh (Cimicifuga racemosa) and St. John's wort (Hypericum perforatum) in women with climacteric symptoms, and to assess their effects on vaginal atrophy, hormone levels, and lipid profiles. MATERIALS AND METHODS In this double-blind randomized, placebo-controlled, multicenter study, 89 peri- or postmenopausal women experi...

OBJECTIVE To investigate the efficacy of the fixed combination of black cohosh (Cimicifuga racemosa) and St. John's wort (Hypericum perforatum) extracts in women with climacteric complaints with a pronounced psychological component. METHODS In this double-blind randomized placebo-control study, 301 women experiencing climacteric complaints with psychological symptoms were treated with ethanol...

BACKGROUND In Brazil, there are few studies of the metabolic syndrome in the general population, and even fewer studies that establish a correlation between metabolic syndrome and climacteric. OBJECTIVE To determine the prevalence of metabolic syndrome and its components among climacteric women. METHODS Cross-sectional study with 323 climacteric women, divided into two groups: pre and post-...

Ripening is one of the key processes associated with the development of major organoleptic characteristics of the fruit. This process has been extensively characterized in climacteric fruit, in contrast with non-climacteric fruit such as grape, where the process is less understood. With the aim of studying changes in gene expression during ripening of non-climacteric fruit, an Illumina based RN...

Cardiovascular diseases / prevention and control; climacteric; menopause; hormone replacement therapy. The I Brazilian Guideline for the Prevention of Cardiovascular Diseases in Climacteric Women was recently published in the Archives1. The initiative is welcome, but it is evident that, even though it is a joint guideline of the Brazilian Society of Cardiology (SBC) and of the Brazilian Society...

PURPOSE The purpose of this study was to construct a measurement instrument for climacteric symptoms among Korean and Japanese women. METHODS From Dec. 1st of 2003 to March 30th of 2004, in-depth interviews were made with 26 women (15 in Jinju, Korea and 11 in Nagasaki, Japan) aged from 45 to 59 years who had not taken hormone replacement therapy to relieve the climacteric symptoms. A draft q...