We describe an approach and an environment for setting up Wizard of Oz experiments to test multimodal interaction (through mobile devices) for multimedia content delivery. This is based on a metamodel and a reference client-server architecture, whose implementation is discussed. The approach allows progressive refinement of the Wizard of Oz environment into a deployed application, through the u...

The vendor firm’s body of knowledge (BoK) has been considered to be vital in IT outsourcing success since outsourcing is considered as flow of knowledge especially from vendor firms to client firms. However, previous researches mostly focused on the client firms’ perspective and less attention on vendor firms and their knowledge bases. In this paper, we investigated the impact of vendor IT firm...

Diagram-centric applications such as software design tools, project planning tools and business process modelling tools are usually “thick-client” applications running as stand-alone desktop applications. There are several advantages to providing such design tools as web-based or even PDAand mobile phone-based applications. These include ease of access and upgrade, provision of collaborative wo...

Elderly adults face two serious challenges bridging the digital divide. First, many suffer from physical or cognitive disabilities, which inhibit computer use. Second, the “traditional” personal computer interface constitutes a foreign and forbidding paradigm. Consequently, elderly adults are less likely to access the Internet, and this lack of accessibility denies them increased social contact...

Objectives: Clinical reasoning is at the heart of clinical work; it is affected by different field factors. A clear understanding of the reasoning process could solve practitioners' problems on how to make their underlying theories, assumptions and values more explicit. The aim of this research is to understand how clinical reasoning process is formed in the context of occupational therapists w...

In this paper, we analyse and seek to understand the complex relations that occur between clients and consultants during consulting projects. The paper uses ideas from Schön’s model of the “reflective practitioner” to propose a new model conceptualising the client-consultant team as a community of interpretive communities. We show that client and consultant belong to different interpretive comm...

We report a link between Cullin5 (Cul5) E3 ubiquitin ligase and the heat shock protein 90 (Hsp90) chaperone complex. Hsp90 participates in the folding of its client proteins into their functional conformation. Many Hsp90 clients have been reported to be aberrantly expressed in a number of cancers. We demonstrate Cul5 interaction with members of the Hsp90 chaperone complex as well as the Hsp90 c...