Injectable depots that respond to exogenous and endogenous stimuli present an attractive strategy for tunable, patient-specific drug delivery. Here, the design of injectable and multimodal degradable hydrogels that respond to externally applied light and physiological stimuli, specifically aqueous and reducing microenvironments, is reported. Rapid hydrogel formation was achieved using a thiol-m...

We investigated auditory temporal processing in children with amblyaudia (AMB), a subtype of disorder, via cortical neural entrainment. Evoked responses were recorded to click-trains at slow versus fast (8.5 14.9/sec) rates n = 14 AMB and 11 age-matched controls. Source time-frequency analyses decomposed EEGs into oscillations (reflecting entrainment) stemming from the bilateral cortex. Phase-l...

introduction: it has been shown that joint click, an initial and common finding in internal derangement (id), respond to neither conservative treatment nor surgical intervention. this raises the question as to whether it must be treated in the absence of other pertinent signs and symptoms, so the aim of this study was to investigate and compare the mri findings of tmj in both normal subjects an...

37 38 The capacity of auditory cortex on Heschl’s gyrus (HG) to encode repetitive transients was studied in 39 human patients undergoing surgical evaluation for medically intractable epilepsy. Multi-contact depth 40 electrodes were chronically implanted in grey matter of HG. Bilaterally presented stimuli were click 41 trains varying in rate from 4 Hz to 200 Hz. Averaged evoked potentials (AEPs)...

The capacity of auditory cortex on Heschl's gyrus (HG) to encode repetitive transients was studied in human patients undergoing surgical evaluation for medically intractable epilepsy. Multicontact depth electrodes were chronically implanted in gray matter of HG. Bilaterally presented stimuli were click trains varying in rate from 4 to 200 Hz. Averaged evoked potentials (AEPs) and event-related ...

Relationships between click-evoked otoacoustic emissions (CEOAEs) and behavioral thresholds have not been explored above 5 kHz due to limitations in CEOAE measurement procedures. New techniques were used to measure behavioral thresholds and CEOAEs up to 16 kHz. A long cylindrical tube of 8 mm diameter, serving as a reflectionless termination, was used to calibrate audiometric stimuli and design...

Numerous fish species produce broad-band pulsed sounds with a distinct temporal patterning which is thought to be important during intraspecific communication. In order to determine whether fishes are able to utilize temporal characteristics of acoustic signals, time resolution was determined in four species of otophysines and anabantoids by analyzing auditory brainstem responses (ABRs) to doub...

中井 義 尚 ・高折 修二 The effects of central depressants on the evoked potential and ensued rhythmic after-discharges in the auditory cortex by a series of single click stimuli in cats were previously reported (1). In contrast to a progressive depression of the evoked potential by urethane and ethyl alcohol, the intravenous infusion of pentobarbital sodium, chlo ralose and chlorpromazine produced consi...