Cancer is one of the leading causes non-communicable diseases in world. In 2015, about 8.8 million cancer deaths worldwide and lung was most common type highest cause death. Therapy for can be either conventional therapy or molecular targeted still has many limitations. It therefore important to explore new sources anticancer activity, including those from plants. One plant that thought have ac...

Exosomes are nanoparticles (carriers) that play vital role in intercellular communication of cells. The present study was aimed at investigating exosomes isolated from biological fluids for their biological applications in disease treatment especially as analgesic drug carrier. Exosomes were isolated from the kidney of cattle through ultracentrifugation of blood, and characterized by inverted s...

Extracts from respective parts and cell cultures of some Turkish medicinal plants have been assessed for their antiviral and cytotoxic properties. None of the extracts tested showed notable activity against herpes simplex viruses (HSV-I and II), but a slight antiretroviral activity against HIV-I was determined in an extract from Hypericum capitatum cell cultures. On the other hand, according to...

Scapholunate dissociation or scaphoid pseudarthrosis may lead to osteoarthritis of the wrist. When osteoarthritis affects the midcarpal joint, proximal row carpectomy is no longer possible and only 4 corners fusion or capitolunate arthrodesis may be indicated. However, in some cases, osteoarthritis or bone necrosis may involve the lunatum, making partial arthrodeses impossible. Total arthrodesi...

Inflammation is a response of vascularized living tissue to the local injury. The severe side effects of steroidal and non-steroidal anti-inflammatory drugs evoked us to search for new anti-inflammatory drugs from the indigenous source. The methanol extract of leaves of Clerodendron infortunatum Linn. (MECI) was evaluated for anti-inflammatory activity against the carrageenan, histamine and dex...

Validation of the ethnotherapeutic claim of Clerodendrum infortunatum L. was investigated to evaluate its wound-healing potency in experimental rats. For topical application, 4% (w/w) ointment cream bases of petroleum ether, chloroform and ethanol extracts were prepared and assessed for their effect on excision, incision and dead space wound models. Significant wound healing was observed in ani...