Structural diversity enables class Ia molecules to present a diverse repertoire of peptides to the T cell receptor. This diversity is thought to be generated by recombinations between class I genes. We have found that two class Ib Q2 alleles exhibit extremely high sequence diversity, even higher than class Ia alleles. Clustered nucleotide differences between Q2b and Q2k suggest that this sequen...

The effect of the Twin Block functional orthodontic appliances is mostly dento-alveolar with small skeletal effect. There are certain clinical indications where functional appliances can be used successfully in class II malocclusion e.g. in a growing patient. The use of these appliances is greatly dependent on the patient's compliance and they simplify the fixed appliance phase. In this case, a...

Skeletal Class II malocclusion is commonly observed clinical entity. A relatively common condition as it is easily recognized by dental health professionals and patients. The dentofacial characteristics with which patient reports to dentist often become an aesthetic and functional handicap for patient [1]. During Angle’s era Class II cases are those with mandibular distoocclusion [2]. According...

classification of occlusion is the first step in diagnosing the relationship between the upper and lower jaw's teeth. based on angle's classification, occlusion is divided into three categories: class i, class ii, and class iii. the aim of this study was to determine the prevalence of occlusion categories, based on angle's classification, in adolescents with permanent dentition in tehran. this ...

Background: Non-Hodgkin lymphoma (NHL) includes a wide range of diseases with different clinical and biological features. NHL is usually presented as localized or generalized lymphadenopathy. It has been suggested that the HLA class I and II are associated with susceptibility to NHL. Different ethnic groups have been found to have different HLA class I and II alleles which affect NHL. Objective...

Bovine viral diarrhea virus (BVDV) is an economically important pathogen of the livestock industry worldwide. BVDV is classified into cytopathic (cp) and noncytopathic (ncp), depending on its effects on cultured cells. BVDV is known to alter the host’s immune response. Of this, major histocompatibility complex (MHC) class II molecules play a central role in the development and function of the i...