نتایج جستجو برای: citrulline

تعداد نتایج: 2203  

Journal: :The Journal of biological chemistry 1957
G H BURNETT P P COHEN

The enzyme carbamyl phosphate-ornithine transcarbamylase, which catalyzes the synthesis of citrulline from ornithine plus carbamyl phosphate, has been partially purified from rat liver by means of heat treatment and ethanol fractionation (1). Krebs et al. (2) were able to demonstrate the arsenolysis of citrulline in a number of tissues and, by using sheep liver mitochondria, were able to purify...

2010
Martijn B Keur Albertus Beishuizen Adriaan A van Bodegraven

Malabsorption as a result of decreased intestinal function is a frequently occurring problem in intensive care units. Small bowel dysfunction may lead to malnutrition and may predispose patients to infectious complications (sepsis) and may be linked to increased hospitalization duration, morbidity and mortality. There are several small bowel function tests, such as faecal fat excretion and suga...

2017
Anke Werner Miriam Koschke Nadine Leuchtner Claudia Luckner-Minden Alice Habermeier Johanna Rupp Christin Heinrich Roland Conradi Ellen I. Closs Markus Munder

In the tumor microenvironment, arginine is metabolized by arginase-expressing myeloid cells. This arginine depletion profoundly inhibits T cell functions and is crucially involved in tumor-induced immunosuppression. Reconstitution of adaptive immune functions in the context of arginase-mediated tumor immune escape is a promising therapeutic strategy to boost the immunological antitumor response...

Journal: :Molecules 2015
Sanne M M Hensen Wilbert C Boelens Kimberly M Bonger Remco T P van Cruchten Floris L van Delft Ger J M Pruijn

Citrullination is the conversion of peptidylarginine to peptidylcitrulline, which is catalyzed by peptidylarginine deiminases. This conversion is involved in different physiological processes and is associated with several diseases, including cancer and rheumatoid arthritis. A common method to detect citrullinated proteins relies on anti-modified citrulline antibodies directed to a specific che...

Journal: :The Journal of Sexual Medicine 2023

Abstract Introduction L-arginine and its precursor, l-citrulline, are two amino acids involved in the production of nitric oxide (NO); as a result, they increase blood flow have been used to treat male sexual dysfunction (Alatas Yagci, 2004). Some lubricants gels contain l-arginine applied directly genital area flow. Although these products evaluated subjectively through patient reports increas...

2015
Alexis Poole Adam Deane Matthew Summers Janice Fletcher Marianne Chapman

INTRODUCTION In this study, we aimed to evaluate whether fasting plasma citrulline concentration predicts subsequent glucose absorption in critically ill patients. METHODS In a prospective observational study involving 15 healthy and 20 critically ill subjects, fasting plasma citrulline concentrations were assayed in blood samples immediately prior to the administration of a liquid test meal ...

Journal: :The Turkish journal of pediatrics 2006
Banu Anlar Kader Karli-Oğuz Osman Yücel Yurtyapan Nesrin Senbil Ozlem Hergüner Sakir Altunbaşak F Müjgan Sönmez Pinar Ozdemir-Geyik

Inherent abnormalities of myelin have been suggested in the pathogenesis of multiple sclerosis (MS). We investigated myelin in acute disseminated encephalomyelitis (ADEM) patients by magnetic resonance spectroscopy (MRS) and cerebrospinal fluid (CSF) analysis for citrulline, a marker of immature myelin. A citrulline peak was observed in the normal appearing white matter of 7/15 patients and of ...

Journal: :Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1997
A Bhardwaj F J Northington L J Martin D F Hanley R J Traystman R C Koehler

We tested the hypothesis that stimulation of metabotropic glutamate receptors (mGluRs) increases nitric oxide (NO) production in the hippocampus in vivo. Microdialysis probes were placed bilaterally into the CA3 region of the hippocampus of adult Sprague-Dawley rats under pentobarbital anesthesia. Probes were perfused for 5 h with artificial cerebrospinal fluid (CSF) containing 3 microM [14C]-L...

Bassami, M, Mahdieh Najafabadi, F, Taghriry, N, Tartibian, B,

Background and Objectives: High blood pressure affects nearly 30% of adults. Inactivity and low intake of antioxidants are associated with increased risks of high blood pressure and cardiovascular diseases. High intensity interval exercise increases blood pressure and oxidative stress. The purpose of this study was to investigate effects of L-citrulline consumption on oxidative stress and antio...

Journal: :Jurnal Gizi dan Pangan Soedirman 2023

The watermelon rind contained 60% higher citrulline than the albedo. Citrulline has benefit of lowering blood pressure.This study aimed to determine effect heating time (albedo) on amino acids, chemical properties (proximate), and organoleptic properties. This conducted using a randomized complete block design (RCBD). treatment wear for 35, 40, 45, 50 minutes. results showed that had no signifi...

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