Atopic dermatitis is an inflammation of the skin, characterized by intense itchiness and dryness of the skin. A rash, flaking and lichenization of the skin are the common characteristics of subjects affected by this disease. The diagnosis is essentially clinical. It is a chronic condition which frequently becomes acute to the extent that we can distinguish between acute and chronic phases. The ...

Background & Aims: Dry type localized cutaneous Leishmaniasis due to Leishmania tropica is one of the most prevalent cutaneous parasitic infections in Kerman province. It seems that cellular immune response and the nature of immune inflammatory cells comprising the inflammatory background play a determinant role in this infection. Methods: Skin biopsies of 53 patients with acute(<2 years durati...

Atopic dermatitis (AD) is a chronic immune-mediated disease characterized by intense pruritis, causing inflammation, itching, and redness of the skin. Dupilumab human monoclonal antibody that has been approved for treatment atopic dermatitis. It also linked with various adverse effects, most them confined to injection site. Café-au-lait-macules are benign pigmented lesions skin, usually seen in...

Sir, Chronic graft-versus-host disease (GVHD) occurs in approximately 60 – 80% of patients who survive for 100 days after allogeneic bone marrow transplantation (BMT) (1). The skin is affected in almost all cases of chronic GVHD, with two distinct phases: the early chronic phase, characterized by lichenoid lesions similar to lichen planus, and the late chronic phase, with sclerodermatous lesion...

background: pegylated interferon and ribavirin are currently one of the accepted treatment for chronic hepatitis c. dermatologic complications of interferon have been reported, but to date a few cases of bacterial cellulitis; a rare and severe complication, have been published. cellulitis is a common infectious process affecting the skin and subcutaneous tissues which results in significant mor...

discussion we have to stress that the importance of this case report is its presentation in an elderly patient, as the frequent age of presentation in the iranian patients is the middle age. on the other hand, pv occurs rarely, thus, the reporting of any rare case with some exceptions is important. case presentation we reported a case of pemphigus vulgaris in a 79-year-old patient with the exte...

Discoid lupus erythematosus (DLE) is a chronic autoimmune disease that primarily affects the skin, causing red, scaly patches may be disfiguring and can cause permanent scarring. This study aimed to investigate potential clinical therapeutic applications of heme oxygenase-1 (HMOX1) in context DLE. Immunohistochemical staining bioinformatics analysis were performed on skin biopsy samples from DL...

Abstract Background: Atopic dermatitis is a common skin disease associated with chronic inflammation in the skin and itches and most patients have a positive family history of dermatitis. The major treatment of dermatitis, based on allopathic medicine, includes symptomatic treatment by oral antihistamines and topical or oral corticosteroids, which, in lo...

We encountered a patient with methylmalonic aciduria associated with skin lesions resembling acrodermatitis enteropathica. This child was being fed with a low-protein diet when the skin disorder developed. A deficiency in plasma levels isoleucine, was confirmed. Supplementation of a high-caloric, protein-rich diet led to a prompt improvement of skin lesions. We assume that in our patient the sk...