OBJECTIVE The aim of the study was to investigate the incidence of chronic kidney disease in patients with T1a renal cell carcinoma both before and after partial or radical nephrectomy, and to assess risk factors for chronic kidney disease. METHODS From January 2001 to December 2011, 1928 patients with a single renal mass ≤4 cm undergoing partial nephrectomy or radical nephrectomy with the ex...

OBJECTIVE To examine the association between key susceptibility factors and measures of chronic kidney disease in Asian American and Native Hawaiian participants enrolled in the Hawai'i site of the national Kidney Early Evaluation Program (KEEP-2) study community screening program. DESIGN In 2001-2003, 793 participants from five ethnic groups (Japanese, Native Hawaii an, Chinese, Filipino and...

Fabry disease (FD) arises from an X-linked defect in lipid storage, whereby deficient or absent lysosomal α-galactosidase A (α-gal A) activity leads to systemic deposition of glycosphingolipids, mainly globotriaosylceramide (known as Gb3 or GL3). Deposition mainly affects the cardiovascular, renal, and neurologic systems, but can occur in all organs, and despite specific enzyme replacement ther...

Objective: Physical activity and herbal medicine can inhabit apoptosis with two different mechanisms. The aim of this study was to assess the combined effect of regular aerobic exercise with garlic extract on heart apoptosis regulatory factors in aged rats with chronic kidney disease. Materials and Methods: In this experimental research, 42 aged male Wistar rats (48-52 weeks) were selected and...

Chronic kidney disease (CKD) is a global health problem, with prevalence of approximately 13 [...]

Hyperuricemia management in chronic kidney disease is a challenging task. We encounter this dilemma on regular basis. Kidney patients have wide range (CKD population, Hemodialysis & peritoneal dialysis cohort and renal transplant patients).

Background and aims: Chronic kidney disease (CKD) is a public health challenge worldwide, with adverse consequences of kidney failure, cardiovascular disease (CVD), and premature death. Chronic kidney disease leads to the end stage of renal disease (ESRD), if late/not diagnosed. Competing risk modeling is a major issue in Epidemiology research. In Epidemiology study, sometimes inappropriate met...

The morbidity and mortality from COVID-19 are particularly high among patients with underlying health disease conditions chronic disease, which kidney transplant recipients (KTRs) [...]

Orthostatic hypotension is associated with cardiovascular disease and mortality, but little is known of its association with incident chronic kidney disease. We evaluated this association in the Atherosclerosis Risk in Communities study. Orthostatic hypotension was defined as a decrease in systolic blood pressure ≥ 20 mm Hg or a decrease in diastolic blood pressure ≥ 10 mm Hg within 2 minutes o...