Background and Aims: Recently, a novel DNA virus was isolated from the serum of a patient with post-transfusion non A-G hepatitis and named TT virus. The aim of this study was to determine the prevalence TT virus among cirrhotic patients due to hepatitis B & C in infection Ahwaz. Methods: The prevalence of TTV infection was studied in 41 patients with liver cirrhosis. TTV DNA was detected ...

background : hepatitis b virus (hbv) and hepatitis c virus (hcv) infections are major global public health problems. this study was conducted to investigate the incidence rate of these infections over six successive years in hamadan province, the west of iran. methods: this retrospective cohort study was conducted on the database of hepatitis registry. in this study, 1257 subjects infected by h...

conclusions we introduced an anti-hbsp antibodies elisa, designed for locally circulating hbv strains. correlation observed of anti-hbsp with liver fibrosis staging regardless of viral replication and liver inflammation suggests anti-hbsp antibodies as possible indicator for hbv-associated liver fibrosis. results seven out of eighty (9%) chb patients were positive for anti-hbsp antibodies. mean...

در سالهای اخیر پیشرفتهای چشمگیری در تشخیص و درمان هپاتیت مزمن ب به دست آمده  و هر چند سال یک بار تغییر و تحولات قابل توجهی در نحوه درمان چنین بیمارانی به دنبال داشته است. اگرچه در چند سال اخیر راهنماهای درمانی متعددی برای هپاتیت مزمن ب در سطح دنیا ارائه شده است(5-1)، با گذشت زمان و انجام تحقیقات جدید، تفاوتهایی بین راهنماهای درمان قابل مشاهده می شود. علاوه بر این بسیاری از داروهای جدید قیمت بسی...

BACKGROUND Oxidative stress can be defined as an increase in oxidants and/or a decrease in antioxidant capacity. There is limited information about the oxidative status in subjects with hepatitis B virus infection. We aimed to evaluate the oxidative status in patients with various clinical forms of chronic hepatitis B infection. METHODS Seventy-six patients with hepatitis B virus infection, i...

conclusions elevated aminotransferases in chb patients are most commonly caused by exacerbation of chb. nevertheless, when hbv dna is not elevated, other reasons should be excluded. amongst others, superinfection with another hepatotropic virus can be the reason for decompensation of chronic hepatitis b. this case report describes an asymptomatic hev superinfection followed by a flare in hbv re...

background and aims: hepatitis d virus (hdv) can infect human population either as a superinfection or concurrent hepatitis b virus (hbv) infection. it is expected that presence of hdv infection is more prevalent in endemic hbv areas. overall 5% of iranian general populations are chronic hbv carriers. the aim of this study was to determine the seroprevalence of hdv and its clinical impact in a ...

Hepatitis G virus/GB virus-C (HGV/GBV-C) is a newly identified Flavivirus. Its clinical significance in chronic hepatitis B and C remains controversial. Infection with HGV/GBV-C was surveyed in 500 blood donors, 130 patients with chronic hepatitis B and 173 with hepatitis C, with chronic liver disease, cirrhosis, and/or hepatocellular carcinoma (HCC). HGV/GBV-C RNA was detected by reverse trans...

An increasing number of patients with chronic hepatitis B infection are being treated with the newly licensed drug, adefovir. It is an acyclic nucleoside phosphonate that is relatively safe in the dosage generally used for chronic hepatitis B. Serious adverse cutaneous drug reactions like Stevens-Johnson syndrome (SJS) or toxic epidermal necrolysis (TEN) following adefovir use have not been rep...