background: chromosomal disorders are the most common cause of first trimester spontaneous abortion. among the human chromosomes, chromosome no.9 was the most common structural chromosomal variant and it is not thought to be of any functional importance, which often considers as a normal variation in structural polymorphisms, nevertheless there are some studies which claim that there is an asso...

The Philadelphia chromosome (Ph') is of particular interest because of its close association with chronic granulocytic leukaemia. Ph' is a distinct chromosome abnormality which is found in the marrow or blood cells of nearly all patients with this leukaemia, and appears to be generally specific to this or closely related disorders. Because of these features, Ph', unlike the chromosome abnormali...

Background and Objectives: studying chromosomal changes for anemia patients of children age (3month-12years ) in the city kut diagnosing those abnormalities resulting from having Methods: The chromosomes Patients to were analyzed studied using cytogenetic analysis detect aberrations caused by after collecting blood samples Al-Karama Teaching Hospital as well clinics Kut.Results: Chromosomal all...

abstract background: acute meyloid leukemia (aml) in adults is known to be a heterogeneous disease with diverse chromosome abnormalities. some of these chromosome abnormalities are found with a high incidence in populations from specific geographical areas and ethnic societies. therefore, we studied the cytogenetic features of aml cases in contrasting societies of iran and india. methods: cytog...

in this study, chromosome analyses were performed on 70 infertile azoospermic and oligospermic (<20 million/ml) men, and also cultures of peripheral blood lymphocytes by high resolution banding method were analysed as well. it is revealed 8 (11.43 percent) men with chromosomal abnormality. there were 31.4 percent patients with azoospermia and 68.6 percent with oligospermia from several thousand...

Although chronic myeloid leukemia (CML) is characterized by the Philadelphia (Ph) chromosome, which is the result of t(9;22) (q34;q11) or its variants, 10%-20% of cases have additional cytogenetic abnormalities. The most common additional abnormalities are loss of the Y chromosome, +8, +Ph, and i(17q). Since these additional chromosome abnormalities are signs of disease progression, it is impor...

background: the infertility is an important health problem, affecting about 15% of couples. the important role of genetic factors in pathogenesis of infertility is now increasingly recognized. the value of karyotyping women in the routine work-out of couples referred for sterility has long been recommended. objective: the aim of this study was to define the frequency of all chromosomal aberrati...

Cytogenetic studies of 91 consecutive patients with therapy-related myelodysplasia or overt acute nonlymphocytic leukemia disclosed characteristic defects of chromosome 7 in 48 cases and of chromosome 5 in 21 cases. The chromosome 5 abnormalities were consistently present in all abnormal mitoses at the time of diagnosis, as were the chromosome 7 abnormalities in 45 of the 48 patients. Various a...

Chromosome anomalies belong to genetic factors, which participate on etiology of reproductive failure. The aim of the study was to investigate the frequency of chromosome abnormalities in infertile men in the Prešov region in Slovakia (1998-2014). Karyotyping using G-banding and C-banding methods was performed in 1426 subjects including 948 infertile men and 478 controls. Karyotype analyses rev...

Structural rearrangements of chromosome 1p have been reported previously as a frequent finding in human neuroblastomas. In a review of karyotypes from 35 neuroblastomas (including 29 published cases and 6 unpublished tumors and cell lines), it was found that, in addition to the abnormalities of chromosome 1p (found in approximately 70% of cases), abnormalities involving only 2 other chromosome ...