The nanoparticle drug delivery system, which uses natural or synthetic polymeric material as a carrier to deliver drugs to targeted tissues, has a broad prospect for clinical application for its targeting, slow-release, and biodegradable properties. Here, we used chitosan (CTS) and hepatoma cell-specific binding molecule glycyrrhetinic acid to synthesize glycyrrhetinic acid-modified chitosan (G...

Abstract Three-dimensional printing technologies exhibit tremendous potential in the advancing fields of tissue engineering and regenerative medicine due to precise spatial control over depositing biomaterial. Despite their widespread utilization numerous advantages, development suitable novel biomaterials for extrusion-based 3D scaffolds that support cell attachment, proliferation, vasculariza...

The present study aims to enhance the bioavailability of Blueberry by formulating it as nanosuspension. mainly consists ofanthocyanins which have strong antihyperlipidemic activity but suffers from low causes hindrances in itstherapeutic treat hyperlipidemia. Hence improve its bioavailability, nanosuspension blueberry was prepared. BoxBehnken design applied predict effect independent variables ...

Objective: The purpose of this study was to determine the optimum formula diltiazem HCl-loaded chitosan nanoparticles due variations in speed and duration stirring evaluating release kinetics vitro using DDSolver.
 Methods: method used prepare is ionic gelation. gelation involves an cross-linking between cations on backbone anion, such as sodium tripolyphosphate (Na TPP). 
 Results: S...

Development of vaccines in autoimmune diseases has received wide attention over the last decade. However, many vaccines showed limited clinical efficacy. To enhance vaccine efficacy in infectious diseases, biocompatible and biodegradable polymeric nanoparticles have gained interest as antigen delivery systems. We investigated in mice whether antigen-encapsulated PLGA (poly-lactic-co-glycolic ac...

The present study aimed to prepare A. goniocephala chloroform extract and evaluate antioxidant cytotoxic effects. Then, the nanoparticles (NPs) were synthesized on most efficient extracts biological activities of free forms compared with NPs forms. Antioxidant capacities 14 by column chromatography found FRAP, DPPH CUPRAC methods. Again, all fractions evaluated MCF-7 HT-29 cell lines using XTT ...