to d ia ic st s, e as w n us of y ic id e ry yAbstract: Molecular epidemiology is the study of genetic and enviro mental risk for disease, with much effort centered on cancer. Childhoo leukemia occurs in nearly a third of all patients newly diagnosed with p diatric cancer. Only a small percentage of these new cases of childhood le kemia are associated with high penetrant hereditary cancer syndr...

A simple and direct analysis of the spatial distribution of childhood leukemia was performed using geographic data from a large case/control study. The data consist of cases of childhood leukemia and their corresponding birth cohort controls located in seven San Francisco Bay Area counties. Both parametric and randomization analyses show no evidence of a non-random spatial pattern of childhood ...

Background: Leukemia is the most common childhood cancer. This cancer, considering its unknown cause(s), is considered as one of the most important health problems amongst children worldwide. The present study was aimed to determine the relationship between breastfeeding and leukemia in Sistan and Baluchestan province, southeast of Iran. Materials and methods: This case-control study was imple...

Benzene is an established cause of adult leukemia, but its role in childhood leukemia is less clear. In a recent meta-analysis, we identified associations of childhood leukemia with occupational and household product benzene exposure and traffic-related pollution. Residential proximity to gasoline stations or automobile repair facilities may be another source of benzene, and in 3 studies assess...

Background: Leukemia is a growing disease. The risk factors such as parental age, cousin marriage, exposure to pesticides and radiation, parental smoking, breastfeeding, and the number of older siblings are suggested as the risk factors for childhood leukemia. Objective: To evaluate the possible risk factors for childhood leukemia, including environmental, parental, genetic and other factors. M...

Background: The purpose of this study is to investigate the genotype and allele distribution MTHFR rs1801133 in Chinese population, analyze relationship between gene polymorphism risk childhood leukemia.
 Methods: Blood samples clinical data leukemia cases (n=1132) age-matched healthy controls (n=1053) were collected. Genotypes detected by PCR-RFLP. Logistic regression model was generated ...

background: malignant neoplasms remain the second leading cause of death in children after accidents. the aim of this study was to assess the epidemiology of childhood cancer in children admitted to dr sheikh hospital, iran. materials and methods: this descriptive cross- sectional study had been done in dr sheikh hospital in mashhad university of medical science on 1764 children younger than 14...

Acute lymphocytic leukemia (ALL) is one of the frequent malignancies in pediatrics and involves bone marrow and extramedullary sites. Proptosis as extramedullary involvement of leukemia usually present in acute and chronic myeloid leukemia. It is extremely rare for ALL to present initially as proptosis.Here, a-21-month-old boy was presented with proptosis without any associated symptoms except ...

INTRODUCTION In some instances, the understanding of the ocular manifestations in childhood leukemia is not only important to establish the diagnosis but also reflects the disease state and prognosis. OBJECTIVE To study the ocular manifestations of childhood acute leukemia among the children attending a tertiary-level hospital in Nepal. MATERIALS AND METHODS A cross-sectional, descriptive s...