BACKGROUND Early life development may influence subsequent respiratory morbidity. The impact of factors determined in childhood on adult lung function, decline in lung function and chronic obstructive pulmonary disease (COPD) was investigated. METHODS European Community Respiratory Health Survey participants aged 20-45 years randomly selected from general populations in 29 centres underwent s...

BACKGROUND AND OBJECTIVES Identifying childhood determinants of adult cardiometabolic disease would facilitate early-life interventions. There are few longitudinal data on the contribution of childhood infections. Therefore, we investigated whether hospitalization with childhood infection is associated with adult anthropometric and metabolic outcomes in a large, well-phenotyped longitudinal coh...

OBJECTIVES To correlate cardiovascular risk factors (e.g., hypertension, obesity, hypercholesterolemia, hypertriglyceridemia, hyperglycemia, sedentariness) in childhood and adolescence with the occurrence of cardiovascular disease. SOURCES A systematic review of books and selected articles from PubMed, SciELO and Cochrane from 1992 to 2012. SUMMARY OF FINDINGS Risk factors for atheroscleros...

introduction:childhood obesity is a major public health crisis nationally and internationally. the prevalence of  childhood obesity has increased over few years. it is caused by imbalance between calorie intake and calories utilized. one or more factors (genetic, behavioral, and environmental) cause obesity in children. physical, psychological, and social health problems are caused due to child...

Childhood asthma is influenced by multiple factors including genetic, socioeconomic, socio demographic and environmental factors. The symptoms of childhood asthma are observed to be variable. Some studies reported that asthma prevalence is disproportionately high among socially disadvantaged children. On the other hand, some reports found weak or no association between social disadvantage and c...

The causes of childhood cancer have been systematically studied for decades, but apart from high-dose radiation and prior chemotherapy there are few strong external risk factors. However, inherent risk factors including birth weight, parental age, and congenital anomalies are consistently associated with most types of pediatric cancer. Recently the contribution of common genetic variation to et...

BACKGROUND It has been suggested that in addition to genetic factors, fetal and post-natal growth influence childhood cognition, although it is unclear whether such an effect continues throughout childhood. This study aimed at investigating the potential relationships between childhood IQ at age 11 years and birth weight and height at the ages of 9 and 13 years, after adjusting for the confound...

Increased arterial stiffness is an independent predictor of cardiovascular disease and mortality in middle-aged and older adults. However, limited data are available regarding the relationship of arterial stiffness in young adults with risk factors measured in childhood, adulthood, or as a cumulative burden from childhood to adulthood. This aspect was examined in a sample of 835 black and white...

Increased arterial stiffness is an independent predictor of cardiovascular disease and mortality in middle-aged and older adults. However, limited data are available regarding the relationship of arterial stiffness in young adults with risk factors measured in childhood, adulthood, or as a cumulative burden from childhood to adulthood. This aspect was examined in a sample of 835 black and white...

BACKGROUND The independent influence of childhood social circumstances on health in later life remains uncertain. We examined the extent to which childhood socio-economic circumstances are related to the risk of coronary heart disease (CHD) in older British men, taking account of adult social class and behavioural risk factors. METHODS A socio-economically representative sample of 5552 Britis...