I N A PREVIOUS REPORT (1), a postulate based on chemical concepts was described which forms the basis of a study of certain steroids possessing seroflocculating properties. The primary objective of the research is the uncovering of a reagent to assist in the diagnosis of disease, perhaps for types of cancer. Secondarily, if that goal is not reached, a reagent suitable for use in a health cleara...

The first chemical incorporation of the boronic acid group into DNA using a copper-free click reagent was reported. Compared with the PCR-based method, this approach allows for site-specific incorporation and synthesis on a larger scale.

The first member of a novel class of chemoselective reagents, glycosyl methanedithiosulfonates, has been synthesized, identified and employed in the first examples of chemical, site-selective construction of a trisulfide-modified protein with complete conversion.

Trudinger, P. A. (Division of Plant Industry, Canberra, Australia). Effect of thiol-binding reagents on the metabolism of thiosulfate and tetrathionate by Thiobacillus neapolitanus. J. Bacteriol. 89:617-625. 1965.-Iodoacetamide, N-ethyl maleimide (NEM), p-chloromercuribenzoate (CMB), Mercurochrome, and HgCl(2) inhibited the oxidation of thiosulfate to sulfate by Thiobacillus neapolitanus; tetra...

Electrochemical cascades are an attractive tool for use in organic synthesis, providing elegant pathway one-pot synthesis of important chemical feedstocks. These cascade reactions typically consist electrochemical redox event that enables several (two or more) subsequent spontaneous reactions. While classic require stoichiometric amounts reagents, especially reactive methods replace reagents wi...

We report a method that uses the process of selective withdrawal of one fluid through a second immiscible fluid to coat small particles with polymer films. Fluid is withdrawn through a tube with its orifice slightly above a water-oil interface. Upon increasing the flow rate, there is a transition from a state where only oil is withdrawn to a state where the water, containing the particles to be...

Indirect UV-absorption spectrometry was shown to be a valuable tool for chemical characterization of functionalized carbon nanotubes (CNTs). It complements data from X-ray photoelectron spectroscopy (XPS) or FTIR analysis since it helps to clarify the type and concentration of functional groups. The principles of indirect application of UV-spectrometry and its mathematical interpretation are di...

Laccase activity and stability were improved and modified through the interaction between laccase amino acid residues (e.g., amino groups (NH2) and carboxyl groups (-COOH)) and the chemical reagents thiourea dioxide (TDO) and L-phenylalanine methyl ester hydrochloride (L-PME). Compared with the control sample, the activity of the laccase modified with these chemical reagents was increased by 20...

This paper describes the utilization of giant unilamellar vesicles (GUVs) as a platform for handling chemical and biochemical reagents. GUVs with diameters of 5 to 10 µm and containing chemical/biochemical reagents together with inert polymers were fused with electric pulses (electrofusion). After reagent mixing, the fused GUVs spontaneously deformed to a budding shape, separating the mixed sol...