نتایج جستجو برای: chemical process safety
تعداد نتایج: 1865805 فیلتر نتایج به سال:
The safe operation of a semi-batch catalytic reactor remains a sensitive issue when highly exothermic side reactions may occur, and various elements such as controllability, stability, safety, and economic aspects have to be considered in the process development. Nominal operating conditions are set to avoid excessive thermal sensitivity to variations in the process parameters. Several shortcut...
Processing (eg, cooking, grinding, drying) has changed the composition of food throughout the course of human history; however, awareness of process-formed compounds, and the potential need to mitigate exposure to those compounds, is a relatively recent phenomenon. In May 2015, the North American Branch of the International Life Sciences Institute (ILSI North America) Technical Committee on Foo...
In this work, we present a novel framework that comprises four stages of process modeling and multiobjective decision-makings considering monetary and non-monetary aspects. Four stages in early design phases are considered and characterized by the available information for process modeling and assessment. Appropriate modeling methods, and evaluation indicators for economy, life-cycle environmen...
This article provides support in organizing and implementing novel concepts for enhancing safety on a cluster level of chemical plants. The paper elaborates the requirements for integrating safety management systems of chemical plants situated within a so-called chemical cluster. Recommendations of existing Plant Safety Management System Codes of Good Practice are analyzed in relation to the ne...
We examine the placement of safety stocks in a supply chain for which we have an evolving demand forecast. Under assumptions about the forecasts, the demand process, and the supply chain structure, we show that safety stock placement for such systems is effectively equivalent to the corresponding well-studied problem for systems with stationary demand bounds and base stock policies. Hence, we c...
Background and aims In the most chemical process industries, workers are exposed to various chemicals and working with these chemicals without considering safety and health considerations can lead to different harmful symptoms. For deciding about control measures and reducing risk to acceptable level , it is necessary to assess the health risk of exposing to harmful chemicals by aid of specif...
Improving the prediction of chemical toxicity is a goal common to both environmental health research and pharmaceutical drug development. To improve safety detection assays, it is critical to have a reference set of molecules with well-defined toxicity annotations for training and validation purposes. Here, we describe a collaboration between safety researchers at Pfizer and the research team a...
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