Neglected Diseases T hrough its impact on worker productivity, premature disability, and death, Chagas disease accounts for 670,000 disability-adjusted life years per annum [1]. This makes it the most important parasitic disease of the Americas. It is both a disease of poverty (Figures 1 and 2) and, like other neglected tropical diseases, also " poverty promoting " [2]. Traditionally confined t...

Abstract Herein we characterize Trypanosoma cruzi infections from blood and CSF samples in a case series of people with HIV Chagas disease. We identify different infecting T. populations highlighting qPCR usefulness for disease reactivation diagnosis evaluation treatment response.

Chagas disease (CD) is endemic to Latin America; its prevalence is highest in Bolivia. CD is sometimes seen in the United States and Canada among migrants from Latin America, whereas it is rare in Europe. We report 9 cases of imported CD in France from 2004 to 2006.

1 Chief, Chagas Disease National Program, Ministry of Health, Maracay, Aragua, Venezuela 2 Program in International Medicine, Universidad de Barcelona, Barcelona, Spain 3 Pediatrics Service, 4 Infectious Diseases Service, 5 Pediatric Cardiology Service, Centro Clínico San Cristóbal, San Cristóbal, Táchira, Venezuela 6 Hematology Service, 7 Pathology Service, Hospital Central de San Cristóbal, S...

The primary objective of this study was to estimate the prevalence of this disease in women of childbearing age and children treated at health centres in underserviced areas of the city of Buenos Aires. Demographic and Chagas disease status data were collected. Samples for Chagas disease serology were obtained on filter paper and the reactive results were confirmed with conventional samples. A ...

INTRODUCTION Honduras has a high prevalence of Trypanosomacruzi infection. The purpose of this study was to assess the knowledge and attitudes of Chagas disease in 17 geographically proximal rural Honduran communities. These communities are under the same local health ministry and are served by yearly medical relief efforts. La Hicaca (LH), although impoverished, is wealthier than the surroundi...

OBJECTIVES To determine whether dobutamine stimulation in patients with Chagas' disease may uncover abnormal contractile responses as seen in ischemic myocardium. BACKGROUND Segmental left ventricular (LV) dysfunction in the absence of coronary atherosclerosis is frequently seen in patients with chronic Chagas' heart disease. Myocardial ischemia and coronary microcirculation abnormalities hav...