In this study the role of adenosine A1 receptors of the CA1 region of hippocampus on piriform cortex–kindled seizures was investigated in rats. Obtained results showed that in kindled animals, bilateral microinjection of N6–cyclohexyladenosine (CHA), an adenosine A1 receptor agonist, at doses of 10 and 100 mM into the hippocampal CA1 region decreased the afterdischarge duration (ADD), stage 5 s...

introduction: the role of adenosine a1 receptors of the amygdala on entorhinal cortex kindled seizures was investigated. material and methods: animals were kindled by daily electrical stimutation of entorhinal cortex. in the full kindled animals, n6-cyclohexyladenosine (cha 10, 50, 100, 500óm), an adenosine a1 receptor agonist and 8-cyclopentyl- 1, 3, dimethylxanthine (cpt, 10, 20 óm), an adeno...

Duck plague virus (DPV), a member of alphaherpesvirus sub-family, can cause significant economic losses on duck farms in China. DPV Chinese virulent strain (CHv) is highly pathogenic and could induce massive ducks death. Attenuated DPV vaccines (CHa) have been put into service against duck plague with billions of doses in China each year. Researches on DPV have been development for many years, ...

Guanine nucleotides, divalent cations, and sodium differentially regulate agonist and antagonist binding to adenosine A1 receptors in brain membranes. Guanine nucleotides decrease the binding of the adenosine A1 receptor agonist [3H]N6-cyclohexyladenosine ([3H]CHA) to guinea pig and bovine brain membranes by about 50% at 1--3 microM, while not affecting binding of the antagonist [3H]1,3-diethyl...

INTRODUCTION AND OBJECTIVES The risk of stroke in atrial fibrillation is heterogeneous and depends upon underlying clinical conditions included in current risk stratification schemes. Recently, the CHA(2)DS(2)-VASc score has been included in guidelines to be more inclusive of common stroke risk factors seen in everyday clinical practice, and useful in defining "truly low risk" subjects. We aime...

BACKGROUND The CHA(2)DS(2)-VASc (Congestive heart failure, Hypertension, Age ≥75 years, Diabetes mellitus, previous Stroke/transient ischemic attack [TIA], Vascular disease, Age 65-74 years, and Sex category [female gender]) schema recently has been introduced to complement the CHADS(2) (Congestive heart failure, Hypertension, Age >75 years, Diabetes mellitus, and previous stroke or TIA) score ...

Antioxidant activities of four kinds of Japanese traditional fermented tea, Gishi-cha, Ishizuchi-kurocha, Awa-bancha, and Batabatacha, were compared. Antioxidant activity was evaluated by three parameters: copper ion reduction ability, radical trapping ability, and oxygen consumption rate. Processes of fermentation of these fermented teas are different. Goichi-cha and Ishizuchi-kurocha are prod...

Highly crystalline carbonated hydroxyapatite (CHA) nanorods with different carbonate contents were synthesized by a novel hydrothermal method. The crystallinity and chemical structure of synthesized nanorods were studied by Fourier transform infrared spectroscopy (FTIR), X-ray photo-electronic spectroscopy (XPS), X-ray diffraction (XRD), Raman spectroscopy, and transmission electron microscopy ...

Aims. In our ongoing search for close and faint companions around T Tauri stars in the Chamaeleon star-forming region, we here present observations of a new common proper motion companion to the young T-Tauri star and Chamaeleon member CT Cha and discuss its properties in comparison to other young, low-mass objects and to synthetic model spectra from different origins. Methods. Common proper mo...

The oxidation of NO to NO2 and the subsequent reduction by NH3 via a NO+ intermediate over proton-type chabazite zeolite (H-CHA) were investigated combination in situ infrared (IR) spectroscopy density functional theory (DFT) calculations. IR spectral results indicate that species formed under flow + O2 at 27–250 °C are more stable lower temperatures both H-CHA copper-cation-exchanged CHA (Cu-C...