Sinus histiocytosis with massive lymphadenopathy (SHML) is a nonneoplastic, usually self limiting disease of unknown aetiology [1]. SHML most commonly presents as painless cervical lymphadenopathy with frequent involvement of other lymph nodes. In 30% of patients extranodal sites such as skin, bone, eye, and breast are involved [2]. Evidence of various immunological dysfunctions has also been d...

Rosai-Dorfman disease is a self-limiting condition caused by histiocyte proliferation within the sinusoids of lymph nodes and in extranodal tissue. It is a rare disease, particularly in children, that progresses with extensive lymphadenopathy. This paper reports on the case of a 2-year-old child with progressive cervical lymphadenopathy associated with persistent fever and radiological findings...

Any patient with bilateral lymphadenopathy especially in Indian subcontinent is regarded as suffering from tuberculosis unless proved otherwise. This sometimes leads to unwarranted delay in correct diagnosis and management if there is ignorance regarding other rarer etiologies. Rosai-Dorfman Disease (RDD) may present in the same manner and should always be kept on the back of the mind to help a...

Kikuchi-Fujimoto disease is a self-limited of unknown etiology that clinically defined by fevers accompanied tender posterior cervical lymphadenopathy. It often presents acutely or sub-acutely, and due to its non-specific features, the differential diagnosis broad includes infectious, autoimmune, malignant causes. Although cases extra-cervical are not uncommon, involvement retroperitoneal lymph...

Metastatic cervical lymphadenopathy is a common problem in head and neck oncology. The appropriate management of the cervical lymph nodes requires a good understanding of the incidence, patterns, and prognostic implications of nodal metastasis. This paper correlates the anatomical and the simplified level classification systems of cervical lymph nodes, examines the clinical significance of noda...

A 70-year-old male presented with multiple lymphadenopathy and a strong clinical suspicion of non-Hodgkin’s lymphoma. Cervical and axillary nodes were excised and were sent for histopathological evaluation, which revealed aggregates of lepra cells loaded with lepra bacilli. Clinicians practising in leprosy endemic areas should keep lepromatous lymphadenitis in mind while investigating patients ...

The aim of study is to know the etiology of cervical lymphadenopathy and to study clinical presentation and clinical course and management of cervical lymphadenopathy. Patients And Methods The study was conducted in government general hospital /Guntur Medica! College, Guntur between the period of 3 years i.e. from November 2012 to October2014. The present study includes 72 patients in both outp...

Kikuchi-Fujimoto disease is a rare, benign, and self-limiting condition that mostly affects young females. Cervical lymphadenopathy with fever is the most common presentation of the disease. It may have unusual presentations that can lead to diagnostic dilemma and delay in diagnosis. We report a case of a 25-year-old female who presented with relapsing fever and cervical lymphadenopathy. Becaus...

Cervical bilateral lymphadenopathy is a frequent event during chronic lymphocytic leukemia (CLL) natural history. However, lymph node biopsy is generally not required as long as transformation into an aggressive lymphoma (Richter syndrome) is not suspected. We present here a rare case of CLL patient who developed progressive bilateral cervical lymph node and bilateral tonsillar hypertrophy. CLL...