Objective: To observe the protective effect of zingiber officinale against radio frequency (RF) radiation-induced oxidative stress on rat brain due to 3G mobile phone. Study Design: Prospective Experimental study. Setting: Department Anatomy, BMSI, JPMC, Karachi. Period: January March 2018. Material & Methods: Twenty four healthy, adult, Albino rats, 3-4 months age, weighing 150-300 gm were...

catecholamine is a group of neurotransmitters that is believed to be responsible for the normal function of animal brain. physiological and behavioral changes of human body have been reported due to the damage of the brain function following lead exposure. due to the assumption of lead disposal in brain tissue with two year for its half-life, which results in alteration of brain function, we in...

background: learning and memory are the most intensively studied subjects in neuroscience. two sites of mammalian brain which are important in learning and memory are ca1 region of hippocampus and purkinje cell layer of cerebellum. so, the aim of present investigation was to study of the effect of ovariectomy and passive avoidance learning on nr1 subunit of n-methyl-d-aspartate (nmda) receptor ...

Objective(s): The aim of the present study was to evaluate antioxidant and methyl donor effects of betaine in cerebellum following levodopa and benserazide administration in rats. Materials and Methods: Sprague-Dawley male rats were treated with levodopa (LD), betaine (Bet), levodopa plus betaine (LD/Bet), levodopa plus benserazide (LD/Ben), levodopa plus betaine-benserazide (LD/Bet-Ben), and t...

Introduction: The neurotoxic effects of aluminum exposure during the critical period of neurodevelopment have been well documented. This study investigated the known protective effects of calcium supplementation on the cerebellum of juvenile Wistar rats following aluminum-induced neurotoxicity during lactation. Methods: Four groups of juvenile rats were exposed via lactation to distilled water...

the variations of glucose 6-phosphate dehydrogenase (g6pd) activity in different brain regions of normal, hypo- and hyperthyroid rats were investigated. hypo- and hyperthyrodism were experimentaly induced by administration of methimazol and liothyronine, respectively. in normal rats, midbrain had the minimum (70 mu/mg) and cerebral cortex the maximum (349 mu/mg) g6pd activity. hyperthyrodism in...

The macromolecular composition of the cerebellum was examined in young and old mice, and in staggerer mutant mice, as compared with their background control strain. We examined the in vitro translation products of cerebellum mRNA, which reflect the biosynthetic potential of cell bodies endogenous to the cerebellum. Simultaneously, we examined the composition of the major cerebellum proteins, wh...