objective: garlic (allium sativum) has anti-inflammatory, anti-mutagenesis, and immunomodulatory properties that modulate anti-tumor immunity and inhibit tumor growth. in this study we have examined the effect of a protein fraction isolated from fresh garlic on anti-tumor response and intra-tumor lymphocyte infiltration. materials and methods: in this experimental study a protein fraction was p...

Atezolizumab plus carboplatin-etoposide (ACE) represents the new first-line (1L) standard of care for extended stage (ES) Small Cell Lung Cancer (SCLC) patients (pts). This is a single-center retrospective-prospective translational study aiming at investigating correlation immune cell distribution and their spatial metrics in tumor samples ES SCLC pts receiving ACE as 1L treatment, with respons...

two omega-3 fatty acids including docosahexaenoic acid (dha) and eicosapentaenoic acid (epa) are essential for the physiologic function of neuronal cell membrane. normal function of neuronal cell membrane requires appropriate composition of fatty in its structure. present study was designed to compare the effect of short-term and long-term pretreatment with omega-3 fatty acids on scopolamine-in...

purpose: to report the clinical and histopathological features of recurrent atypical fibrous histiocytoma of the corneo-scleral limbus followed by intra-epithelial squamous neoplasia. case report: a 25-year-old female patient presented with a recurrent vascularized gelatinous mass in the left nasal limbus. the preliminary histopathological diagnosis of the previously excised lesion was an amela...

Introduction: Hunger and reduction in regular energy intake can lead to a number of problems based on their intensity. For instance, low energy level can cause blood cell production to decline or it may pose a higher risk of anemia. It can also weaken the immune system and platelet aggregation or negatively affect clot formation. This study aimed to have a closer look at fasting and regular phy...

objectives this study aimed at reviewing the current literature on the diagnosis, staging, and different treatment strategies for wilms’ tumor with either ureteral or intravascular extension. evidence acquisition in this article, we reviewed the current literature about staging, diagnosis, and management strategies for wt, through a randomized clinical trial, which focused on this matter. the m...