نتایج جستجو برای: cd4 t cells
تعداد نتایج: 1919622 فیلتر نتایج به سال:
background: cd4+ and cd8+ t cells are the main types of lymphocytes in cell-mediated immunity and play a central role in the induction of efficient immune responses against tumors. the frequencies of t cell subtypes in the peripheral blood and tumor tissues, and draining lymph nodes (dln) can be considered as useful markers for evaluation of the immune system in cancers. methods: in this study,...
variety of positive as well as negative regulatory signals are provided by antigen presenting cell in particular by dendritic cells. in this research, we studied the capacity of dendritic cells to expand antigen-specific t regulatory cells.we also investigated the role of tgf-beta in induction inhibitory functions of dendritic cells in mixed leukocyte reactions. dendritic cells were generated f...
In the article was studied effects of flavonol quercetin on indices adaptive immune response in experimental animals 14 th day bacterial-immune periodontitis development. Indices protection were determined by relative number lymphocytes with CD3+, CD4+, CD8+, CD19+, CD16+ and immunoregulatory index (CD4+ / CD8+) intact inflammatory process development periodontal tissues as well therapeutic que...
Background and purpose: Crohn disease (CD) is an autoimmune disorder in which a failure of tolerance to the intestinal antigens plays a pivotal role in the pathogenesis of this disease. Treg cells control immune responses to self and foreign antigens and have an important role in maintaining self-tolerance. In this study we evaluated the frequency of Tregs in the peripheral blood of patients wi...
NK/T-cell ratios predict disease activity in relapsing remitting multiple sclerosis (RRMS). We investigated 50 RRMS patients whether interleukin-2 receptor alpha-chain (IL-2R?) expression and shedding associates with balance, as suggested by daclizumab-trials RRMS. A subsample (N = 31) was genotyped for IL2RA-associated MS risk SNPs. CD56bright NK-cell/IL-17A+CD4+ T-cell correlated negatively p...
multiple sclerosis (ms) is an autoimmune disease in which auto-reactive t cells react with self-antigens expressed in the central nervous system (cns). the main cause of ms is unknown. nonetheless, the most probable theory is based on molecular mimicry, which suggests that some infections can activate t cells against brain auto-antigens like myelin proteolipid protein (plp) and initiate the dis...
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