CONTEXT Clinical, endoscopic, radiological and histological parameters of intestinal tuberculosis (IT) and Crohn's disease (CD) are so similar that differentiation between these two diseases, which require different treatment, is difficult. Anti- Saccharomyces cerevisiae antibody (ASCA), which is often present in the sera of patients with CD, may be potentially useful to differentiate CD from I...

OBJECTIVE To identify, purify, and characterize the proteins responsible for glutenase activity in the feces of healthy subjects and patients with celiac disease (CD). METHODS Sixteen subjects were included in this study; 8 were healthy with no known food intolerances, and 8 were treated CD patients on a gluten-free diet. Fecal samples were homogenized, and precipitated proteins were purified...

AIMS To identify specific gut bacteria associated with coeliac disease (CD) at diagnosis and after treatment with a gluten-free diet (GFD) in a paediatric population. METHODS 30 and 18 faecal samples from untreated and treated CD patients and 25 and 8 biopsy samples from untreated and treated CD patients, respectively, were analysed. In addition, 30 faecal and 8 biopsy samples from control ch...

OBJECTIVE The prevalence of celiac disease (CD) as recorded in the Danish National Patient Registry is ∼50/100,000 persons. This is much lower than the reported prevalence of CD in other Nordic countries and underdiagnosis is suspected. Our aim was to estimate the prevalence of CD in a population-based study of Danish adults. METHODS A total of 2297 adults aged 24-76 years living in the south...

Abstract Background The development and availability of Janus kinus inhibitors (JAKinibs) for moderately to severely active ulcerative colitis (UC) provides new therapeutic options with both novel mechanisms unique pharmacodynamic benefits. Tofacitinib (tofa) is a non-selective pan-JAKinib that received FDA approval UC in 2018 upadacitinib (upa) JAK-1 selective inhibitor, 2022. It unknown wheth...

The crystal structure of the title compound, [Cd(2)Cl(2)(C(2)H(8)N(2))(4)]Cl(2), consists of binuclear centrosymmetric [Cd(2)(C(2)H(8)N(2))(4)Cl(2)](2+) cations and discrete chloride anions. The Cd(II) cation is coordinated by four N atoms of two ethyl-enediamine ligands and two symmetry-related chloride anions within a distorted CdN(4)Cl(2) octa-hedron. Two Cd(II) cations are connected by two ...