BACKGROUND AND PURPOSE Comprehensive cardiac rehabilitation (CCR), which integrates structured lifestyle interventions and medications, reduces morbidity and mortality among cardiac patients. CCR has not typically been used with cerebrovascular populations, despite important commonalities with heart patients. We tested feasibility and effectiveness of 6-month outpatient CCR for secondary preven...

Abstract Real-world classification domains, such as medicine, health and safety, finance, often exhibit imbalanced class priors have asynchronous misclassification costs. In cases, the model must achieve a high recall without significantly impacting precision. Resampling training data is standard approach to improving performance on binary data. However, state-of-the-art methods ignore local jo...

BACKGROUND Equations for estimating glomerular filtration rate (GFR) have not been validated in Sub-Saharan African populations, and data on GFR are few. METHODS GFR by creatinine clearance (Ccr) using 24-hour urine collections and estimated GFR (eGFR) using the four-variable Modification of Diet in Renal Disease (MDRD-4)[creatinine calibrated to isotope dilution mass spectrometry (IDMS) stan...

4 Ramsey’s Theorem 12 4.1 Definitions and Classical Version . . . . . . . . . . . . . . . . 13 4.2 Recursive Analogue is False . . . . . . . . . . . . . . . . . . . 15 4.3 How Hard is it to Tell if a Homogeneous set is Recursive? . . . 16 4.4 Recursion-Theoretic Modifications . . . . . . . . . . . . . . . . 19 4.5 Connections to Proof Theory . . . . . . . . . . . . . . . . . . 23 4.6 Miscellane...

Purpose:Despite therapeutic advances, non–Hodgkin lymphomas (NHL) remain incurable. They form a group of neoplasms strongly dependent on their inflammatory microenvironment, which plays an important supportive role in tumorB-cell survival and in the resistance to antitumor immune response.New therapies must consider both tumor cells and their surrounding microenvironment Experimental Design: St...

Dasatinib is a small molecule tyrosine kinase inhibitor that targets a wide variety of tyrosine kinases implicated in the pathophysiology of several neoplasias. Among the most sensitive dasatinib targets are ABL, the SRC family kinases (SRC, LCK, HCK, FYN, YES, FGR, BLK, LYN, and FRK), and the receptor tyrosine kinases c-KIT, platelet-derived growth factor receptor (PDGFR) a and b, discoidin do...

Introducción: El carcinoma de células renales (CCR) representa el 80-90% todos los cánceres riñón con una edad máxima incidencia entre 60-70 años. Los tres síntomas más comunes son hematuria, dolor en costado y masa costado. La mejor opción tratamiento para la enfermedad renal crónica es trasplante renal. uno factores riesgo del CCR. mayoría casos se diagnostican después un renal; diagnóstico d...